ID   A0A101VY91_9PROT        Unreviewed;       163 AA.
AC   A0A101VY91;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Cation:proton antiporter {ECO:0000313|EMBL:KUO63147.1};
GN   ORFNames=APF80_06300 {ECO:0000313|EMBL:KUO67134.1}, APF80_13970
GN   {ECO:0000313|EMBL:KUO63147.1};
OS   Alphaproteobacteria bacterium BRH_c36.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria.
OX   NCBI_TaxID=1734406 {ECO:0000313|EMBL:KUO63147.1, ECO:0000313|Proteomes:UP000053382};
RN   [1] {ECO:0000313|EMBL:KUO63147.1, ECO:0000313|Proteomes:UP000053382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRH_c36 {ECO:0000313|EMBL:KUO63147.1};
RA   Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA   Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT   "Microbial metabolic network in the subsurface.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E
CC       family. {ECO:0000256|ARBA:ARBA00006228}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO63147.1}.
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DR   EMBL; LOEV01000089; KUO63147.1; -; Genomic_DNA.
DR   EMBL; LOEV01000041; KUO67134.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101VY91; -.
DR   STRING; 1734406.APF80_06300; -.
DR   Proteomes; UP000053382; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002758; Cation_antiport_E.
DR   PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR   PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR   Pfam; PF01899; MNHE; 1.
DR   PIRSF; PIRSF019239; MrpE; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        61..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   163 AA;  18024 MW;  06360F7F0D0BDD49 CRC64;
     MLRAVLPHPL LALTLVVVWT LLFNSFTPGT IVTGIIVAIS VTKFTSVYWP SDTRVRNPRE
     IIAYMAVFLW DIVLSNIQVA RLVLFRSGDR LKSRFVTVPL DVTSPEAIVA LAATITLTPG
     TLSVDVAADN RSIIVHCLDV DDPDALVAGI KERYELRLKR ILT
//