ID   A0A101WCF2_9FIRM        Unreviewed;       413 AA.
AC   A0A101WCF2;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=ROK family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN   ORFNames=APF77_17590 {ECO:0000313|EMBL:KUO70613.1};
OS   Clostridia bacterium BRH_c25.
OC   Bacteria; Bacillota; Clostridia.
OX   NCBI_TaxID=1734399 {ECO:0000313|EMBL:KUO70613.1, ECO:0000313|Proteomes:UP000057710};
RN   [1] {ECO:0000313|EMBL:KUO70613.1, ECO:0000313|Proteomes:UP000057710}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRH_c25 {ECO:0000313|EMBL:KUO70613.1};
RA   Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA   Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT   "Microbial metabolic network in the subsurface.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC       {ECO:0000256|ARBA:ARBA00002486}.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO70613.1}.
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DR   EMBL; LOES01000200; KUO70613.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101WCF2; -.
DR   STRING; 1734399.APF77_17590; -.
DR   Proteomes; UP000057710; Unassembled WGS sequence.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   413 AA;  45767 MW;  617A08662D25295B CRC64;
     MDKYQNKGGN TAIIKKNNLS LIVRLIREMG VVSRTELSRI TDLSKGGLTP IIQELIEKNV
     IRETGVIDSA VGRKPIVLEI NSNISYVIAV DINRSKMQIG LVNFTNQLQS FYEYKYAAKE
     TAQEIVKRLK SMIRFFIDQN QDKHIAAIAV SVPGPLNYQN GIILNPPNFE GWENLNIKAL
     LEEEFGISTI LDKDANAYAM AEKTVGLGKK YKNFIHITHC EGVGSGIVLN DKLYRGVDGF
     GTEIGHIIVD FNGKQCDCGN KGCLEKYASM NAIIEWIESK LGSDTDKAND PIRTVYERSG
     RIEWDDVIDG LAKHVPICLE AMENAGTYLA YSLVSMINIF APEAIIIGGP SVLVGKYLLK
     PIKKIIAARS FFRDYYLSDV LLSELKDGAL IGIAGIAFEH LLNDSIEILL GND
//