ID A0A101WU89_9CREN Unreviewed; 354 AA.
AC A0A101WU89;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=threonine ammonia-lyase {ECO:0000256|ARBA:ARBA00012096};
DE EC=4.3.1.19 {ECO:0000256|ARBA:ARBA00012096};
DE Flags: Fragment;
GN ORFNames=AT714_04335 {ECO:0000313|EMBL:KUO79330.1};
OS Vulcanisaeta sp. OSP_8.
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Vulcanisaeta.
OX NCBI_TaxID=1714252 {ECO:0000313|EMBL:KUO79330.1, ECO:0000313|Proteomes:UP000054992};
RN [1] {ECO:0000313|EMBL:KUO79330.1, ECO:0000313|Proteomes:UP000054992}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jay Z.J., Beam J.P., Kozubal M.A., Jennings R.D.E., Rusch D.B.,
RA Inskeep W.P.;
RT "The distribution, diversity and function of predominant Thermoproteales in
RT high-temperature environments of Yellowstone National Park.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO79330.1}.
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DR EMBL; LOCF01000125; KUO79330.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101WU89; -.
DR Proteomes; UP000054992; Unassembled WGS sequence.
DR GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006567; P:threonine catabolic process; IEA:InterPro.
DR CDD; cd04886; ACT_ThrD-II-like; 1.
DR CDD; cd01562; Thr-dehyd; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR044561; ACT_ThrD-II-like.
DR InterPro; IPR005789; Thr_deHydtase_catblc.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01127; ilvA_1Cterm; 1.
DR PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF01842; ACT; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS51671; ACT; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Branched-chain amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Isoleucine biosynthesis {ECO:0000256|ARBA:ARBA00022624}.
FT DOMAIN 277..354
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KUO79330.1"
SQ SEQUENCE 354 AA; 37560 MW; 576359148834093E CRC64;
PKVRGAYFAI NNAVRDMKVN HVVTASAGNH AQGVAYSASL LGIKATVVMP QYTPWIKIAR
TRRYGADVVL HGESYTEAEE YATGLAKELG AYYVHAYNDL DVIAGQGTIG LEVLEDLKDI
DYVVVPVGGG GLISGIASVI KTVSPRTKVI GVQSEGAPGA YLSLKSGRII TVERVDTIAD
GIAVKRIGDL TFKLMSELLD DIVLVNDLEI AKAILMIAES VKVIAEGAGA AAVAALISGK
VRVSGNVVAI VSGGNIDMNL LFRVISKALA IEGRIIKISG LLPDRPGMLG RVTTVLGELG
VNILDVLHER YDPTITPGYA EVSFIVELPP EEGALDKVMR KLGELGFNFR VEKP
//
