ID A0A101XF47_9CREN Unreviewed; 368 AA.
AC A0A101XF47;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:KUO90203.1};
GN ORFNames=AT708_03585 {ECO:0000313|EMBL:KUO90203.1};
OS Pyrobaculum sp. OCT_11.
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=1714259 {ECO:0000313|EMBL:KUO90203.1, ECO:0000313|Proteomes:UP000054659};
RN [1] {ECO:0000313|EMBL:KUO90203.1, ECO:0000313|Proteomes:UP000054659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jay Z.J., Beam J.P., Kozubal M.A., Jennings R.D.E., Rusch D.B.,
RA Inskeep W.P.;
RT "The distribution, diversity and function of predominant Thermoproteales in
RT high-temperature environments of Yellowstone National Park.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO90203.1}.
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DR EMBL; LOBY01000087; KUO90203.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101XF47; -.
DR Proteomes; UP000054659; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21123; SPASM_MftC-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04053; TIGR04053 family radical SAM/SPASM domain-containing protein; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR PANTHER; PTHR11228:SF34; TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE COFACTOR MODIFYING PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 12..229
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 368 AA; 41027 MW; 0C9F7AF68F9C5FA8 CRC64;
MKNVKELIAR FYTAPLLVFW ESTKACPLTC KHCRADAILK PLPGELTTAE GKRLIDQVAE
FGDPKPLLII TGGDPLMRRD LWELVDYANA AGVPVSLAPA VSPNLDEETL KEVRAHGVKS
ISISLDGAGP ETHDELRGVP GSFHDTVKSI KTAVEVGVPV QVNTVVWRKS LPELPEVVKL
LKDLGVKVWE VFFLIVTGRA KEELDITPEQ YEAAVQFLVD VSTYGVQIRT VEAPFYRRAK
LERLEGKTYD HPLHRHLTER LRKLLGPPTR GVDPTIVPTR DGFGIIFVAY DGTVHPSGFL
PYPLGNVRRQ SLVQIYREHP LLQKMRRGEL GGRCGVCRYK DVCGGSRARA YAYFKDPLAE
DPACIYRP
//
