ID A0A101XNC4_9BACL Unreviewed; 321 AA.
AC A0A101XNC4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=D-glycerate dehydrogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ATW55_04125 {ECO:0000313|EMBL:KUO94607.1};
OS Ferroacidibacillus organovorans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Ferroacidibacillus.
OX NCBI_TaxID=1765683 {ECO:0000313|EMBL:KUO94607.1, ECO:0000313|Proteomes:UP000053557};
RN [1] {ECO:0000313|EMBL:KUO94607.1, ECO:0000313|Proteomes:UP000053557}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITV001 {ECO:0000313|EMBL:KUO94607.1,
RC ECO:0000313|Proteomes:UP000053557};
RA Dall'Agnol H., Nancucheo I., Johnson B., Oliveira R., Leite L., Pylro V.,
RA Nunes G.L., Tzotzos G., Fernandes G.R., Dutra J., Orellana S.C.,
RA Oliveira G.;
RT "Draft genome sequence of Acidibacillus ferrooxidans ITV001, isolated from
RT a chalcopyrite acid mine drainage site in Brazil.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO94607.1}.
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DR EMBL; LPVJ01000072; KUO94607.1; -; Genomic_DNA.
DR RefSeq; WP_067720410.1; NZ_LPVJ01000072.1.
DR AlphaFoldDB; A0A101XNC4; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000053557; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719}.
FT DOMAIN 33..319
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 112..290
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 321 AA; 35143 MW; 8B451B85F4ACF1F8 CRC64;
MTRLKLFVTR QLPRDVCDAV PADVSLAMYE HEKQAIPREE LLARVAGARG IVTMLTERID
EEVMNAAGPQ LAVISTMSVG FEHIDRGAAA QRGIVVCHTP DVLTETTADL VFALLLATAR
QLPQAERALR EGQWGTWQPF QFLGTDVHGK TIGLLGMGGI AQAVARRARG FGMRILYWSR
SRKSDVEETL GVTYSDLTTL LQASDFVVPL LPGGDATRHL IDQHALSRMK RNAMLINASR
GSVVDEDALL QALQTRAIAG AGLDVFAREP IALTHPLLRE ERVVLLPHIG SATLETRTSM
ARRALENALL VMRGEAPFDR V
//
