ID A0A102DE93_9SPHN Unreviewed; 952 AA.
AC A0A102DE93;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:KUR79903.1};
GN ORFNames=AQZ50_03260 {ECO:0000313|EMBL:KUR79903.1};
OS Novosphingobium sp. Fuku2-ISO-50.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1739114 {ECO:0000313|EMBL:KUR79903.1, ECO:0000313|Proteomes:UP000056630};
RN [1] {ECO:0000313|EMBL:KUR79903.1, ECO:0000313|Proteomes:UP000056630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fuku2-ISO-50 {ECO:0000313|EMBL:KUR79903.1,
RC ECO:0000313|Proteomes:UP000056630};
RA Ruckert C., Winkler A., Glaeser J., Grossart H.-P., Kalinowski J.,
RA Glaeser S.;
RT "Draft genome sequence of Novosphingobium sp. Fuku2-ISO-50 (=DSM 27930), a
RT Novosphingobium acidiphilum related species isolated from a surface water
RT sample of the southwest basin of Lake Grosse Fuchskuhle.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUR79903.1}.
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DR EMBL; LLZR01000004; KUR79903.1; -; Genomic_DNA.
DR RefSeq; WP_067742626.1; NZ_KQ954286.1.
DR AlphaFoldDB; A0A102DE93; -.
DR STRING; 1739114.AQZ50_03260; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000056630; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000056630}.
FT DOMAIN 478..561
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 577..835
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 862..944
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 952 AA; 99925 MW; 3EC29B165D2DCB1D CRC64;
MRAGSGIDGE AMRFTFDGKA YWGVDGDTLA AALMANGVRL LARSFKYHRP RGIMAMGVEE
PSALVTLGEG ARAEPNVRAS DVFLYPGLVA TSQNAWPSLR HDVGAVNSLV SALIPAGFYY
KTFFGPPSRW MIYERFIRRA AGLGRPPQGA DPDRYGHRAA FCDVLVVGAG PAGLAAALRA
VEAGRRVILV EQDALPGGSL LRENVTIDGV PGAKWAARAV GRIRAAGGRV LMRTTATGHW
DDNFVTAVER RVEPGQTSRG LAQVLWKLRC GDVILASGAL ERPLVFADND VPGIMLAGAA
RALALRYGVA PGRRAVIATS HDEAYRTAFA LAGLGVEIVA ILDSRVDPQG ALVNAARARF
PVLVDARPLR GLRRGVALAG IDAMVGTTRR RFVADCLAMS GGMSPVLHLH RQAGGALDYD
AARGAFLPGA ARQRQTTVGA AAGEHDLRAI LDLSKIDDPL GPVAPAEPGP IWRGEAHGKA
FVDFQNDVTT ADLALAQREG YVSVEHTKRY TTLGMGTDQG KLGAMVALAQ IADERGLPLP
QAGLTMFRPP YTPVTLGAFA GPARGDHAAP IRRLPLAEAH DDLGALWVPA GAWMRPRAYL
RPGESLGEAS LREARMVRSL AGVVDVSSLA KFEIAGPDAL AVVEAVCATP VARLGVGRGR
YTVMLREDGM VMDDGTLWRL AEDRWLLTSS TGGAARMARH LSYVADILLA RPRAAVINVS
EHWAGLAFAG PRAAGLLAEL TGQPVPAHMG LAQATIAGAP VRVLAASYSG ERAFEVHVPA
YRAAGVFAAL VGAAQGVGGG VYGLDAMDHL RVEKGHVVIG AEADGRAIPA DLGLGGMVRK
SGGFVGWQAL TRPALADCAE RRQLVGVTSI DGAPIPEGAM LVVREGEEPV GHVTTSAPRV
AGEGAIGLGL LVDGGARHGE ALLAWSPTRK QCVSVQVGAP LFYDAEGARY RD
//
