ID A0A103E5T1_9BURK Unreviewed; 267 AA.
AC A0A103E5T1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Ureidoglycolate lyase {ECO:0000256|ARBA:ARBA00019751};
DE EC=4.3.2.3 {ECO:0000256|ARBA:ARBA00012341};
DE AltName: Full=Ureidoglycolase {ECO:0000256|ARBA:ARBA00032843};
DE AltName: Full=Ureidoglycolatase {ECO:0000256|ARBA:ARBA00030302};
DE AltName: Full=Ureidoglycolate hydrolase {ECO:0000256|ARBA:ARBA00029968};
GN ORFNames=WS67_07270 {ECO:0000313|EMBL:KVE28917.1};
OS Burkholderia singularis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=1503053 {ECO:0000313|EMBL:KVE28917.1, ECO:0000313|Proteomes:UP000062788};
RN [1] {ECO:0000313|EMBL:KVE28917.1, ECO:0000313|Proteomes:UP000062788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSV85 {ECO:0000313|EMBL:KVE28917.1,
RC ECO:0000313|Proteomes:UP000062788};
RA Sahl J., Keim P., Wagner D.;
RT "Expanding the genomic diversity of Burkholderia species for the
RT development of highly accurate diagnostics.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-ureidoglycolate = glyoxylate + urea; Xref=Rhea:RHEA:11304,
CC ChEBI:CHEBI:16199, ChEBI:CHEBI:36655, ChEBI:CHEBI:57296; EC=4.3.2.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001281};
CC -!- PATHWAY: Purine metabolism; urate degradation.
CC {ECO:0000256|ARBA:ARBA00004705}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVE28917.1}.
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DR EMBL; LOWA01000018; KVE28917.1; -; Genomic_DNA.
DR RefSeq; WP_059515476.1; NZ_LOWA01000018.1.
DR AlphaFoldDB; A0A103E5T1; -.
DR OrthoDB; 9792137at2; -.
DR UniPathway; UPA00394; -.
DR Proteomes; UP000062788; Unassembled WGS sequence.
DR GO; GO:0018817; F:2-oxo-hept-3-ene-1,7-dioate hydratase activity; IEA:InterPro.
DR GO; GO:0050385; F:ureidoglycolate lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0019628; P:urate catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR InterPro; IPR012690; HpcG.
DR NCBIfam; TIGR02312; HpaH; 1.
DR PANTHER; PTHR30143:SF0; 2-KETO-4-PENTENOATE HYDRATASE; 1.
DR PANTHER; PTHR30143; ACID HYDRATASE; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000062788}.
FT DOMAIN 74..264
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 267 AA; 28956 MW; 311A931847B38641 CRC64;
MLDLTTIDLL ARKLHTAERE RKQIRQISLD HPDITIDDAY AIQRTWVDIK LAEGRVLKGH
KIGLTSKAMQ ASSQIDEPDF GTLLDDMFFD DGATIPTQRF IVPRVEVELA FVLGKPLSGP
GCTLLDVYDA VDYVVPALEI IDARSQSIDP DTKRPRKVFD TIADNAANAG VVIGGRPVRP
TDIDLRWVAA IMSRNGVVEE TGVAAGVLNH PANGVVWLAN RLARFGVTLG AGEIILGGSF
TRPCAAKSGD TFSVDYGPLG AVHCHFE
//
