ID A0A103EIT7_9BURK Unreviewed; 452 AA.
AC A0A103EIT7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Dihydropyrimidine dehydrogenase {ECO:0000313|EMBL:KVE35470.1};
GN ORFNames=WS68_05810 {ECO:0000313|EMBL:KVE35470.1};
OS Burkholderia sp. TSV86.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=1385594 {ECO:0000313|EMBL:KVE35470.1, ECO:0000313|Proteomes:UP000066043};
RN [1] {ECO:0000313|EMBL:KVE35470.1, ECO:0000313|Proteomes:UP000066043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSV86 {ECO:0000313|EMBL:KVE35470.1,
RC ECO:0000313|Proteomes:UP000066043};
RA Sahl J., Keim P., Wagner D.;
RT "Expanding the genomic diversity of Burkholderia species for the
RT development of highly accurate diagnostics.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVE35470.1}.
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DR EMBL; LOWB01000075; KVE35470.1; -; Genomic_DNA.
DR RefSeq; WP_059571066.1; NZ_LOWB01000075.1.
DR AlphaFoldDB; A0A103EIT7; -.
DR Proteomes; UP000066043; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR PANTHER; PTHR43073; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR PANTHER; PTHR43073:SF2; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
FT DOMAIN 33..63
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 452 AA; 47083 MW; 86DC0DADCE731FF5 CRC64;
MSWKEIGDVA AGRLPAAQLA CNFADVAPPL DTGAARVAAD RCHYCYDAPC VAACPTGIDI
PGFIRKIGNG NLRGAARDIL SANPLGGMCA RVCPTEILCE GACVRHHQDG EPVEIGALQR
YATDWQLARE AAGEKPLFER AAPSGKRVAV IGAGPAGFAC AHGLARAGHD VVIFDTHGKP
GGLNEYGIAA YKTVDGFAQR EAAWLMSIGG IEWRANQTLG RELTLDALRA EFGAVFVGVG
LAGVNALRIE GEALDGVIDA VDFIARLRQA DDLSQVSVGR RVVVIGGGNT AVDAAVQSRK
LGALQVTIAY RRGTMQMSAT GAEREFAQRN GVTLIEWARP ARIVGDGGRV SGVEFDAMRA
TPAGGVEPTG DTFRIDADVV LKAIGQRFEP GGLAAPLALD GGRIAVDAQG ATSLPGVWAG
GDCTNHAGED LTVQAVEDGK RAARAIDRFL RG
//
