ID   A0A103ERJ0_9BURK        Unreviewed;       346 AA.
AC   A0A103ERJ0;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=lipopolysaccharide heptosyltransferase II {ECO:0000256|ARBA:ARBA00044042};
DE            EC=2.4.99.24 {ECO:0000256|ARBA:ARBA00044042};
GN   ORFNames=WS68_22220 {ECO:0000313|EMBL:KVE39466.1};
OS   Burkholderia sp. TSV86.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=1385594 {ECO:0000313|EMBL:KVE39466.1, ECO:0000313|Proteomes:UP000066043};
RN   [1] {ECO:0000313|EMBL:KVE39466.1, ECO:0000313|Proteomes:UP000066043}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TSV86 {ECO:0000313|EMBL:KVE39466.1,
RC   ECO:0000313|Proteomes:UP000066043};
RA   Sahl J., Keim P., Wagner D.;
RT   "Expanding the genomic diversity of Burkholderia species for the
RT   development of highly accurate diagnostics.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-
CC         [alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-
CC         (1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid
CC         A + H(+); Xref=Rhea:RHEA:74071, ChEBI:CHEBI:15378, ChEBI:CHEBI:61506,
CC         ChEBI:CHEBI:193068, ChEBI:CHEBI:193069, ChEBI:CHEBI:456216;
CC         EC=2.4.99.24; Evidence={ECO:0000256|ARBA:ARBA00043830};
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 9 family.
CC       {ECO:0000256|ARBA:ARBA00043995}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KVE39466.1}.
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DR   EMBL; LOWB01000021; KVE39466.1; -; Genomic_DNA.
DR   RefSeq; WP_059569530.1; NZ_LOWB01000021.1.
DR   AlphaFoldDB; A0A103ERJ0; -.
DR   Proteomes; UP000066043; Unassembled WGS sequence.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR   CDD; cd03789; GT9_LPS_heptosyltransferase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR002201; Glyco_trans_9.
DR   InterPro; IPR011910; RfaF.
DR   NCBIfam; TIGR02195; heptsyl_trn_II; 1.
DR   PANTHER; PTHR30160:SF7; ADP-HEPTOSE--LPS HEPTOSYLTRANSFERASE 2; 1.
DR   PANTHER; PTHR30160; TETRAACYLDISACCHARIDE 4'-KINASE-RELATED; 1.
DR   Pfam; PF01075; Glyco_transf_9; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KVE39466.1}.
SQ   SEQUENCE   346 AA;  37932 MW;  F482829168FEE696 CRC64;
     MRRALVIAPN WIGDALMAQP LFALLKKLHP RIVIDAVAPA WVAPVLERMP EIHDVHATDL
     AHGKLQPLRR WQLASDLRDV GYDAAYVLPN SLKSALIPWM AGIALRIGYT GEHRYGLLNV
     RHANPAKARD ARPPMVEHYA ALAYAPGAKL PDAQKTLPPP RLDADLNETA RVCARFNLDT
     RKPLIVFCPG AEYGPAKRWP PEHFAALAQS VSQSFPYTQI VALGSPKDAA AAQAIAERAP
     NVKSLCGQTS LSEACALIAR ANAVVTNDSG LMHVAAALRR PLIALYGSTD PRHTPPLSEL
     AKVQWLHLEC SPCFERECPL GHLNCLRELS PEQVFSDLRG MLVEQR
//