ID A0A103XNB7_CYNCS Unreviewed; 776 AA.
AC A0A103XNB7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=Ccrd_004063 {ECO:0000313|EMBL:KVH93893.1};
OS Cynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Carduoideae; Cardueae;
OC Carduinae; Cynara.
OX NCBI_TaxID=59895 {ECO:0000313|EMBL:KVH93893.1, ECO:0000313|Proteomes:UP000243975};
RN [1] {ECO:0000313|EMBL:KVH93893.1, ECO:0000313|Proteomes:UP000243975}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2C {ECO:0000313|EMBL:KVH93893.1};
RX PubMed=26786968; DOI=10.1038/srep19427;
RA Scaglione D., Reyes-Chin-Wo S., Acquadro A., Froenicke L., Portis E.,
RA Beitel C., Tirone M., Mauro R., Lo Monaco A., Mauromicale G., Faccioli P.,
RA Cattivelli L., Rieseberg L., Michelmore R., Lanteri S.;
RT "The genome sequence of the outbreeding globe artichoke constructed de novo
RT incorporating a phase-aware low-pass sequencing strategy of F1 progeny.";
RL Sci. Rep. 6:19427-19427(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVH93893.1}.
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DR EMBL; LEKV01004587; KVH93893.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A103XNB7; -.
DR STRING; 59895.A0A103XNB7; -.
DR EnsemblPlants; KVH93893; KVH93893; Ccrd_004063.
DR Gramene; KVH93893; KVH93893; Ccrd_004063.
DR OMA; ETDHHER; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000243975; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR47446; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR PANTHER; PTHR47446:SF2; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51698; U_BOX; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000243975};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 14..89
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 742..776
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 776 AA; 86673 MW; 482F8A33831144AF CRC64;
MEEIESQIGG GNHTPPKDFV CPITTLVFSD PVTLETGQTY ERKAIQKWIE RGNSTCPVTH
QKLHSVQLPK TNYVLKRLIS SWKELIRRND GFTESQFRNP ENKNENNIPQ LISPKSVISR
ATIDGTINEL RVVITDLCTS QVLEKAEMAV LRIERFWKEV NMEVEIYNML SKPPVINGFV
EILFNSVNTQ VLVTTVFLLS ELGSRDGSVI STLTRVYSDM ECIVALFKKG LFEAVVLIYL
LKPSISSFLQ MDMANALLNA VQKKDNEFLT MCVKPKAASV LLLSQIIASE DDHGAVSEVI
RTLISGKAIE CIIRSLQSDW TDERIAAMRI LLRCIQKDGK CRNMIADKAE LAPVLETFLE
ANDGERMKVL LVQCIHSSYI YKPLSPINAQ LLRAEPRKMS IYREEAIDNL ISCLKNSDTP
RAQIAAAETL LALQGRFSYS GKPLVRKFLL KRVGLDKTDR SMRKEQLAGV SGDVQETMMA
FVLVNHDVGL IFEALSEGLK SRYVEVCSAC FVTATWLLHM LTLLPDTGVQ GAARACLLKR
FVSIFKSAKD TEDKALSMLA LSSFIHDPEL VQEDCGINGA AISIVFCEDK IFSGHSDGMI
KTTKIWTLKG SILRLTHETR EHTKACLALV NGRLYSGCMD NSIQVPKWFM ISDFLSALNL
VIIDLENPFQ EIDLATGTLT SIQNGTRKLL AKANRVNVLQ SVSLTSEVRT MAISSEFIYF
GCKMGIVEVW YRNKVARKET LQTGTNSKVV CMDLNSNEDV LVIGTSDGKI HVWGLN
//
