ID A0A108TBG3_9BACE Unreviewed; 396 AA.
AC A0A108TBG3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Beta-ketoacyl-[acyl-carrier-protein] synthase family protein {ECO:0000313|EMBL:KAA5413815.1};
GN ORFNames=F2Y81_22040 {ECO:0000313|EMBL:KAA5413815.1};
OS Bacteroides cellulosilyticus.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=246787 {ECO:0000313|EMBL:KAA5413815.1, ECO:0000313|Proteomes:UP000448877};
RN [1] {ECO:0000313|EMBL:KAA5413815.1, ECO:0000313|Proteomes:UP000448877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A6 {ECO:0000313|EMBL:KAA5413815.1,
RC ECO:0000313|Proteomes:UP000448877};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA5413815.1}.
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DR EMBL; VVYV01000047; KAA5413815.1; -; Genomic_DNA.
DR RefSeq; WP_007215123.1; NZ_VVYV01000047.1.
DR AlphaFoldDB; A0A108TBG3; -.
DR STRING; 246787.BcellWH2_03909; -.
DR eggNOG; COG0304; Bacteria.
DR Proteomes; UP000448877; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..392
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 396 AA; 43039 MW; 920C10CCEAA6634C CRC64;
MKIYVTGLGV VSGIGLGVAE NIASLRKHQH GMGKVTLFPT ELDVPVSEVK YSNEELKRLL
SLDIQKTFSR TALLGMLAAR EAVDDARLDL NTLRVGLISS TSIGGMDLSE HFYNAFKKDN
RKGRLREVIS HDCGASTEMI ADYLKVNDFV TTISTACSSA ANAIMLGARM IRNGQLDAAI
VGGTDALCKF TLNGFNSLMI LDKEHCRPFD ASRAGLNLGE GAGYIVLQSE KLLRKESYCL
LSGYSNVNEA FHQTGSSPEG NGPFWSMTEA IAKSEIPPEE IDYINVHGTG TPSNDLSEGL
AIRRIFGDKI PPFSSVKAFI GHTLGASEGI EAVYSVLSVY HGFIYPNLNF KEPIEENMLM
PETSFREGLP IRNVLSNSFG FGGNDSSILF STLKEK
//
