ID   A0A109BAR1_HYPSL        Unreviewed;       634 AA.
AC   A0A109BAR1;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Nucleoside-diphosphate sugar epimerase/dehydratase {ECO:0000313|EMBL:KWT65137.1};
GN   ORFNames=APY04_2886 {ECO:0000313|EMBL:KWT65137.1};
OS   Hyphomicrobium sulfonivorans.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Hyphomicrobiaceae; Hyphomicrobium.
OX   NCBI_TaxID=121290 {ECO:0000313|EMBL:KWT65137.1, ECO:0000313|Proteomes:UP000059074};
RN   [1] {ECO:0000313|EMBL:KWT65137.1, ECO:0000313|Proteomes:UP000059074}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WDL6 {ECO:0000313|EMBL:KWT65137.1,
RC   ECO:0000313|Proteomes:UP000059074};
RA   Albers P.;
RT   "Transcriptomic analysis of a linuron degrading triple-species bacterial
RT   consortium.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KWT65137.1}.
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DR   EMBL; LMTR01000082; KWT65137.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A109BAR1; -.
DR   STRING; 121290.APY04_2886; -.
DR   PATRIC; fig|121290.4.peg.486; -.
DR   Proteomes; UP000059074; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059074};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          272..566
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   634 AA;  70067 MW;  0DDFFD6CFDB2441E CRC64;
     MDLALLILAL WIALSIRYNT IYIPPDFAVA LILLSGPLIT VATFAISELY RLVTRYLGYR
     GHTRIIGCIW LSVLIWSLVA FMAGQPAAPP RSVLFGYGIL ATLFITGSRE MISMLLESAG
     VRLSELPADV ERTPVIIFGA GQLGVQLLET LRRGNAREAV AFVDTEPSVW RQYVAGVKVH
     DARRLPSLIE RYHVKEVLVA LPNDRRHERK LILKDLQQQP VQVLTLPDVE DVTSGRVSVA
     DLRRLEVNDL LGRDRVPPDA KLLMRKTQGK SILVTGAGGS IGSELVRQLL KHRPRRIVLF
     ELSEIALYRI NDEVAEVLRG MQPDEPRPEI VGVLGSVCDP TKVREALVDY DVEVIYHAAA
     YKHVPIVEQN PIAGLQNNTF GTAALVEQAQ AAGVELFVLI STDKAVRPTN VMGASKRMAE
     LVLQAAAAKG GPTVFTMVRF GNVLDSSGSV VQKFRRQIKA GGPVTVTHPD IIRYFMSIPE
     AAELVIQAGA MAEGGEVFVL DMGEPVRIDD MARLMVRLSG FDVKDAEKPD GDIAIMYTGL
     RPGEKLYEEL LIGDNTSQTE HPRIWRSDEP FLSEDDLRRQ LSQLSAALET RDLNALHAIL
     LRNVEGYHPE NAVSALPIDD ERARDWPAPS RTLH
//