ID A0A109II05_9ACTN Unreviewed; 507 AA.
AC A0A109II05;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Two-component sensor histidine kinase, contains HisKA and HATPase domains {ECO:0000313|EMBL:SCG79739.1};
GN ORFNames=GA0070623_4748 {ECO:0000313|EMBL:SCG79739.1};
OS Micromonospora rifamycinica.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=291594 {ECO:0000313|EMBL:SCG79739.1, ECO:0000313|Proteomes:UP000198226};
RN [1] {ECO:0000313|EMBL:SCG79739.1, ECO:0000313|Proteomes:UP000198226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44983 {ECO:0000313|EMBL:SCG79739.1,
RC ECO:0000313|Proteomes:UP000198226};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT607752; SCG79739.1; -; Genomic_DNA.
DR RefSeq; WP_067312125.1; NZ_LT607752.1.
DR AlphaFoldDB; A0A109II05; -.
DR OrthoDB; 9767435at2; -.
DR Proteomes; UP000198226; Chromosome i.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.280; GAF domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR038424; H_kinase_PdtaS_GAF_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR022066; PdtaS_GAF.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF23; SENSOR HISTIDINE KINASE PDTAS-RELATED; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF12282; PdtaS_GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SCG79739.1};
KW Transferase {ECO:0000313|EMBL:SCG79739.1}.
FT DOMAIN 302..506
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 507 AA; 54719 MW; E27F8D34F6E19D5C CRC64;
MSTLRDLAEE HTKLRPADID HLHRIAGDWQ LLSDLSFADL LLWVPVDDDG TFLCVAQVRP
TTAPTAYLDD QVGRIVGGPE VAHLEVAYRQ GRIWREGDPV WYGDVPARHE AIPVRLRTAE
GEAGEVIAVV GRDTNLSTAR TPSQLELNYL TTADDLAQMI ADGTFPPPRH PGETTSAPRV
GDGLVRLDAD GKVTYASPNA QSAYRRLGYA SHLVGEDLAK LHRRLASDPL DGTEAANGIL
AALRGEGPPR REIDARGATM LTRALPLMPA GVPIGALVLV RDITEVRRRD RALITKDATI
REIHHRVKNN LQTVAALLRL QARRVSMPEA RVALEESVRR VASIALVHET LSMSSDEAVE
FDGIVDRVAS AATEVAATEV SVGMRRTGSF GVLPAEIATS LVMVLNELLL NAVEHGFPPV
EEGGEAAEPD VRPEVVVSAH RQRKQLHVSV TDNGRGLPAE FDADRGGRLG LQIVRALVTG
ELRGSIELRP GPTGGTEAVL VLPLAKV
//
