ID   A0A109II50_9ACTN        Unreviewed;       327 AA.
AC   A0A109II50;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase {ECO:0000313|EMBL:SCG50489.1};
GN   ORFNames=GA0070623_1818 {ECO:0000313|EMBL:SCG50489.1};
OS   Micromonospora rifamycinica.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=291594 {ECO:0000313|EMBL:SCG50489.1, ECO:0000313|Proteomes:UP000198226};
RN   [1] {ECO:0000313|EMBL:SCG50489.1, ECO:0000313|Proteomes:UP000198226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44983 {ECO:0000313|EMBL:SCG50489.1,
RC   ECO:0000313|Proteomes:UP000198226};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; LT607752; SCG50489.1; -; Genomic_DNA.
DR   RefSeq; WP_067311915.1; NZ_LT607752.1.
DR   AlphaFoldDB; A0A109II50; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000198226; Chromosome i.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR020025; PseB.
DR   NCBIfam; TIGR03589; PseB; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          9..282
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   327 AA;  36385 MW;  FD9E03C02D3F2D6D CRC64;
     MSELNGSSIL ITGGTGSFGK AFLRHVLTVA DPARVVVFSR DELKQYELRQ QLGDDPRLRW
     FIGDIRDRHR LTRAMHGVDH VVHAAALKQV DTAEYNPSEF IATNITGSQH VVDAAIEAGV
     RKVIALSTDK ASSPINLYGA TKLVGDKLFV SANHYAAQHP TRFAVVRYGN VVGSRGSVVP
     LFRRLADEGR SLPITDKRMT RFWITLDQAV QFVLDSFDQM QGGELFVPRI PSMRILDLVE
     AVAPEATTHE IGIRPGEKLH EEMIAPDDSR RTLRAKDRFI VQPTIATWGY QPPVDCEPVP
     DGFAYQSDGN DEWLSVRQLR DMLGITA
//