ID   A0A109IMA2_9ACTN        Unreviewed;       341 AA.
AC   A0A109IMA2;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=O-methyltransferase {ECO:0000313|EMBL:SCG51164.1};
GN   ORFNames=GA0070623_1896 {ECO:0000313|EMBL:SCG51164.1};
OS   Micromonospora rifamycinica.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=291594 {ECO:0000313|EMBL:SCG51164.1, ECO:0000313|Proteomes:UP000198226};
RN   [1] {ECO:0000313|EMBL:SCG51164.1, ECO:0000313|Proteomes:UP000198226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44983 {ECO:0000313|EMBL:SCG51164.1,
RC   ECO:0000313|Proteomes:UP000198226};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT607752; SCG51164.1; -; Genomic_DNA.
DR   RefSeq; WP_067305093.1; NZ_LT607752.1.
DR   AlphaFoldDB; A0A109IMA2; -.
DR   OrthoDB; 3804952at2; -.
DR   Proteomes; UP000198226; Chromosome i.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 1.10.287.1350; -; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR   PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   PIRSF; PIRSF005739; O-mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SCG51164.1};
KW   Transferase {ECO:0000313|EMBL:SCG51164.1}.
FT   DOMAIN          116..320
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
SQ   SEQUENCE   341 AA;  36181 MW;  CBDE6AE22B8A457F CRC64;
     MTIENPTGDD PAARLARLTD LATPFAVRTA VTLRVPERIA AGVTRLDKLA AACDADPDAL
     GRLLRYLAHR GVVVEASPDE FTLTDVGELL CDRDGGGHGA YLDLDGLGAR MDLAYTGLPH
     AVRTGGPGYQ AVHGRDFWAD LDAHPAYRAY FDALMLSQQR FTAPQVAALY PWQQVGHVVD
     VAGGAGGLLR ELLDTHPHLR GTLVDRSEPV ATAARAFAEH GLTGRVDTVV GDFFAELPAG
     ADVYVVSRAL TDWSDAHATA ILRRCAEAAG STGRVLVVEV LPTDPYVPHR SPYDLQMLVL
     VGGRERGVPE HVALAAAAGL APVRTYRGTD GLTLLEFAAA A
//