ID   A0A109JHS6_9BRAD        Unreviewed;       578 AA.
AC   A0A109JHS6;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Dihydroxy-acid dehydratase {ECO:0000313|EMBL:KWV48974.1};
DE            EC=4.2.1.9 {ECO:0000313|EMBL:KWV48974.1};
GN   ORFNames=AS156_16825 {ECO:0000313|EMBL:KWV48974.1};
OS   Bradyrhizobium macuxiense.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=1755647 {ECO:0000313|EMBL:KWV48974.1, ECO:0000313|Proteomes:UP000057737};
RN   [1] {ECO:0000313|EMBL:KWV48974.1, ECO:0000313|Proteomes:UP000057737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BR 10303 {ECO:0000313|EMBL:KWV48974.1,
RC   ECO:0000313|Proteomes:UP000057737};
RA   Zelli J.E., Simoes-Araujo J.L., Barauna A.C., Silva K.;
RT   "Draft Genome Sequence of the Strain BR 10303 (Bradyrhizobium sp.) isolated
RT   from nodules of Centrolobium paraense.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC       {ECO:0000256|ARBA:ARBA00006486}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KWV48974.1}.
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DR   EMBL; LNCU01000104; KWV48974.1; -; Genomic_DNA.
DR   RefSeq; WP_066512904.1; NZ_LNCU01000104.1.
DR   AlphaFoldDB; A0A109JHS6; -.
DR   OrthoDB; 7793094at2; -.
DR   Proteomes; UP000057737; Unassembled WGS sequence.
DR   GO; GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR   InterPro; IPR042096; Dihydro-acid_dehy_C.
DR   InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR   InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR   InterPro; IPR037237; IlvD/EDD_N.
DR   PANTHER; PTHR43183:SF2; DIHYDROXY-ACID DEHYDRATASE; 1.
DR   PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00920; ILVD_EDD; 1.
DR   SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR   SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR   PROSITE; PS00886; ILVD_EDD_1; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:KWV48974.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
SQ   SEQUENCE   578 AA;  63331 MW;  24D9940A681E4961 CRC64;
     MTKNKTPDQL RSARWFAPDD LRAFGHRSRA MQMGYAPEEW RDRPVIAIIN TWSDAQPCHM
     HFKSRVDDVK RGVLMAGGFP MELPALSLSE SLLKPTTMLY RNMLAMDAEE LLRGHPVDGV
     VLMGGCDKTT PALLLGATSM NLPAIYLPAG PMLRGNWKGR TLGSGSDAWK YWDERRAGKI
     SDKDWVDMEA GIARSYGTCM TMGTASTMTA IAESIGMTLP GASSIPAADA NHIRMSSEAG
     RRIVEMVWED LTPQKIQTRQ AFENAITVAM AMGCSTNAII HLIAQARRAG QDISLDDFET
     ASRKVPVIAN VRPSGDRYLM EDFFYAGGLP GLMSRIKDHL HLGCMTASGK TLGENIADAE
     VYNDDVIRDV ANPIYKEGAL AVLKGNLAPD GCVIKPSACD PRFLKHTGPA LVFDDYPSMK
     KAVDDPDLDV TADHVLILRN AGPQGGPGMP EWGMLPIPTK LVKQGVRDMV RLSDARMSGT
     SYGACILHVS PESFIGGPLS LVRNGDRITI DVAARTINLD VPEAELAKRR AAWRAPERRF
     ERGYGWMFSR HIKQANEGCD FDFLETGFGK PVGEPSIY
//