ID A0A109LX28_9SPHN Unreviewed; 272 AA.
AC A0A109LX28;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:KWV95372.1};
GN ORFNames=ASS64_05085 {ECO:0000313|EMBL:KWV95372.1};
OS Erythrobacter sp. AP23.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Erythrobacter/Porphyrobacter group; Erythrobacter.
OX NCBI_TaxID=499656 {ECO:0000313|EMBL:KWV95372.1, ECO:0000313|Proteomes:UP000058666};
RN [1] {ECO:0000313|EMBL:KWV95372.1, ECO:0000313|Proteomes:UP000058666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AP23 {ECO:0000313|EMBL:KWV95372.1,
RC ECO:0000313|Proteomes:UP000058666};
RA Lin W., Zheng Q.;
RT "Draft genome sequence of Erythrobacter sp. AP23.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWV95372.1}.
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DR EMBL; LNBY01000012; KWV95372.1; -; Genomic_DNA.
DR RefSeq; WP_067691341.1; NZ_LNBY01000012.1.
DR AlphaFoldDB; A0A109LX28; -.
DR STRING; 499656.ASS64_05085; -.
DR OrthoDB; 9804790at2; -.
DR Proteomes; UP000058666; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0044281; P:small molecule metabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR018170; Aldo/ket_reductase_CS.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43827; 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE; 1.
DR PANTHER; PTHR43827:SF3; ALDO-KETO REDUCTASE; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PIRSF; PIRSF000097; AKR; 2.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
PE 4: Predicted;
FT DOMAIN 18..257
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
FT ACT_SITE 51
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-1"
FT BINDING 105
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-2"
FT SITE 72
FT /note="Lowers pKa of active site Tyr"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-3"
SQ SEQUENCE 272 AA; 30086 MW; 23A54D1B90B7AEE9 CRC64;
MAEYPTLTLN DGRKIPQLGF GTWQIEEDEA AGAVRTALDV GYWLVDTAAV YGNERGVGEG
IGEWSDIFLQ TKIWNESQGY DRTLKAADKC LERLGRDHVD MLLIHWPCPE KDLFVETWKA
LIELRDQGKA KSIGVSNFRE EDLKRIVDAT GVTPALNQIE LHPGFQQRAL RKVHQEMGVV
TQSWSPLGQG GGMDAGAIQE IAGETGQPPS AVVLRWHIQH GLCPIPKSTS RDHIEQNFAA
LSFELSDDQM ARIDALDDPE GRLGPDPASF EG
//
