ID A0A109MXY8_9BACI Unreviewed; 740 AA.
AC A0A109MXY8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glycosyl hydrolase family 65 {ECO:0000313|EMBL:KWW18195.1};
GN ORFNames=AS888_20310 {ECO:0000313|EMBL:KWW18195.1};
OS Peribacillus simplex.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Peribacillus.
OX NCBI_TaxID=1478 {ECO:0000313|EMBL:KWW18195.1, ECO:0000313|Proteomes:UP000064189};
RN [1] {ECO:0000313|EMBL:KWW18195.1, ECO:0000313|Proteomes:UP000064189}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VanAntwerpen02 {ECO:0000313|EMBL:KWW18195.1,
RC ECO:0000313|Proteomes:UP000064189};
RA Couger M.B.;
RT "Genome Sequence of Bacillus simplex strain VanAntwerpen2.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC {ECO:0000256|ARBA:ARBA00006768}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWW18195.1}.
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DR EMBL; LNNH01000023; KWW18195.1; -; Genomic_DNA.
DR RefSeq; WP_061142476.1; NZ_LNNH01000023.1.
DR AlphaFoldDB; A0A109MXY8; -.
DR Proteomes; UP000064189; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR005194; Glyco_hydro_65_C.
DR InterPro; IPR005195; Glyco_hydro_65_M.
DR InterPro; IPR005196; Glyco_hydro_65_N.
DR InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11051:SF8; PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE; 1.
DR Pfam; PF03633; Glyco_hydro_65C; 1.
DR Pfam; PF03632; Glyco_hydro_65m; 1.
DR Pfam; PF03636; Glyco_hydro_65N; 1.
DR PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KWW18195.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 6..238
FT /note="Glycoside hydrolase family 65 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03636"
FT DOMAIN 299..661
FT /note="Glycoside hydrolase family 65 central catalytic"
FT /evidence="ECO:0000259|Pfam:PF03632"
FT DOMAIN 672..730
FT /note="Glycoside hydrolase family 65 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03633"
FT ACT_SITE 473
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT BINDING 333..334
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT BINDING 573..574
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ SEQUENCE 740 AA; 83996 MW; 04D818256AC44B1D CRC64;
MKKLEENSFD PRYINKFASL MTVGNGYFGL RASHEENYVN QTRGMYVAGI YNKATVNEPS
DLVNLPDVAG MNIELDGEVF SLLTGEILSY KRQLNLENGE LRRDILWKSR TGSRFRLTFQ
RFAAKNDRHV LATKLTVTSL DKPAQMKIVT GIDAQQTNFG RQHLIEEKVR VAEGDLLQGT
YKTTESGHTI AIATCCTGSV KGEMSHTAKN RQLLSAINQN LLADTPFVLE KMSVIFTSLD
GDLRGESPEE ATEAVLRSCS AVGYDALLHK SAGEWAQFWM EKRIKVASTR DFDQLAIDFS
LYQLEVMTPA HDERFSVGAK GLTGEGYKGH VFWDTEIFIT PFHLYTEPEK ARKLLRYRYL
RLKQALDKAA TNGYEGALFP WESAFTGEEE TPEFAAINIK TGKRQKVASA LAEHHIVADI
AYTVVKYYQN TWDDWFMKKE GLELLKETSR FWISRAVEEN DQLVIKDVIG PDEYTEHIDN
NAFTNYMAWY NVEQALFFMD KYGDDDRQLK DRGHEFLKRL YLPKANDDKI IPQDDTFLSK
PEIDLSRYKQ AQGSQGILMD YSRQEVNEMQ ILKQADVVML LYLLPDVFPS DIIYENLRYY
EEHTIHDSSL SKAIHAIVAA RAGEIEKAYE FFQESCLIDL GPNPQSSDEG LHAASLGAIW
MAAMFGFANV SIKNQRLSLD PKLPSGWSEL AFPLIFQGSR LHIALTHNQA VITKVSGDDV
CIELNGTEFL VSDKFAMDLH
//
