ID   A0A109UMZ7_9GAMM        Unreviewed;       590 AA.
AC   A0A109UMZ7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Mechanosensitive channel MscK {ECO:0000313|EMBL:AMD02247.1};
GN   Name=mscK_2 {ECO:0000313|EMBL:AMD02247.1};
GN   ORFNames=LOKO_03201 {ECO:0000313|EMBL:AMD02247.1};
OS   Halomonas chromatireducens.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=507626 {ECO:0000313|EMBL:AMD02247.1, ECO:0000313|Proteomes:UP000063387};
RN   [1] {ECO:0000313|EMBL:AMD02247.1, ECO:0000313|Proteomes:UP000063387}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD02247.1,
RC   ECO:0000313|Proteomes:UP000063387};
RX   PubMed=26988058;
RA   Sharko F.S., Shapovalova A.A., Tsygankova S.V., Komova A.V.,
RA   Boulygina E.S., Teslyuk A.B., Gotovtsev P.M., Namsaraev Z.B.,
RA   Khijniak T.V., Nedoluzhko A.V., Vasilov R.G.;
RT   "Draft Genome Sequence of 'Halomonas chromatireducens' Strain AGD 8-3, a
RT   Haloalkaliphilic Chromate- and Selenite-Reducing Gammaproteobacterium.";
RL   Genome Announc. 4:0-0(2016).
RN   [2] {ECO:0000313|EMBL:AMD02247.1, ECO:0000313|Proteomes:UP000063387}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD02247.1,
RC   ECO:0000313|Proteomes:UP000063387};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP014226; AMD02247.1; -; Genomic_DNA.
DR   RefSeq; WP_066451517.1; NZ_CP014226.1.
DR   AlphaFoldDB; A0A109UMZ7; -.
DR   STRING; 507626.LOKO_03201; -.
DR   KEGG; hco:LOKO_03201; -.
DR   PATRIC; fig|507626.3.peg.3196; -.
DR   OrthoDB; 9792218at2; -.
DR   Proteomes; UP000063387; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.10.287.1260; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000063387};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..590
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007140989"
FT   TRANSMEM        223..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        271..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        299..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        343..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          398..463
FT                   /note="Mechanosensitive ion channel MscS"
FT                   /evidence="ECO:0000259|Pfam:PF00924"
FT   REGION          134..153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          566..590
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   590 AA;  65987 MW;  95DCD19D514C61A8 CRC64;
     MTGNGAWRLW SILAVMAVAI VISGASLAQM PQGAVANGGE SESDSEEKEW FPLDTLNDGL
     DATPDAVRRD TPRESIRSFQ QLTDQEEYAS AAHVLNLSEL DAAEQPQRGA ELARQLAEIL
     RRGEWLDVSD LPGRQDAAIE DPSGQHPQAG EPRRNLELAS LEAKGDTYDI RLARYRVDDE
     DPIWLITPDS VASIPVLYEE FGPSLLEAYI PDRFKTSFGR LQVWEWIAIP VFLMLIGLVG
     WGVYGLVGLL SQWFPNGVPS IFASRIRSPM AFLIMAFVAQ SLLDYVVSFT AVATTFIRIL
     LIIMIAWGVG TIALRLVDTI LLKVTRRMVG EIDDTKPKDE RKLLTTLYAV RRIIILITVA
     AVSVYVLSQI PLFETLGMSL LASASVLAVL VGIAGQAVLG NILSSFQLSL AKPIRIGDLV
     MFEGQWCYVE GIFYTFIRLR SWDERRLIVP VTYFVSKPFE NLSVKSAKMY RTLELVVHLS
     ADTQVIREKF LEYAKEEDNV VEHHRLCCYV TGQSERAQTI SCYLMASDPF AGWVAEMNIR
     ERLMAFIRDN HPEWWPREVV VLSQHDITKG DEPRVRPPSG VESHGGEASE
//