ID A0A109UXM1_9SACH Unreviewed; 209 AA.
AC A0A109UXM1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 20 {ECO:0000256|ARBA:ARBA00019690, ECO:0000256|PIRNR:PIRNR007945};
DE AltName: Full=Mediator complex subunit 20 {ECO:0000256|ARBA:ARBA00031954, ECO:0000256|PIRNR:PIRNR007945};
GN ORFNames=AW171_hschr21013 {ECO:0000313|EMBL:AMD19197.1};
OS Eremothecium sinecaudum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=45286 {ECO:0000313|EMBL:AMD19197.1, ECO:0000313|Proteomes:UP000243052};
RN [1] {ECO:0000313|EMBL:AMD19197.1, ECO:0000313|Proteomes:UP000243052}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58844 {ECO:0000313|EMBL:AMD19197.1,
RC ECO:0000313|Proteomes:UP000243052};
RA Dietrich F.S.;
RT "Genome sequence of the yeast Holleya sinecauda.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. {ECO:0000256|PIRNR:PIRNR007945}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR007945}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 20 family.
CC {ECO:0000256|ARBA:ARBA00010743, ECO:0000256|PIRNR:PIRNR007945}.
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DR EMBL; CP014242; AMD19197.1; -; Genomic_DNA.
DR RefSeq; XP_017986193.1; XM_018130704.1.
DR AlphaFoldDB; A0A109UXM1; -.
DR STRING; 45286.A0A109UXM1; -.
DR GeneID; 28721455; -.
DR OrthoDB; 2041863at2759; -.
DR Proteomes; UP000243052; Chromosome ii.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 3.30.310.180; -; 2.
DR InterPro; IPR016532; Med20.
DR InterPro; IPR013921; Mediator_Med20.
DR Pfam; PF08612; Med20; 1.
DR PIRSF; PIRSF007945; SRB2; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|PIRNR:PIRNR007945};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR007945};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR007945};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR007945}.
SQ SEQUENCE 209 AA; 23518 MW; 12157E48D87698AE CRC64;
MKHTAVIFVE KATTSTVTEF YDALSTHVIS VKEKWSFELK TFRSTVKNLP QDDTKVMHSL
TLTHHDNQTI TLKNQSAIVT GYQVQDQLTS NGCSTGFPEP FDNILISKLS NIWTQRQSIK
GEFGSTYETP EFLVRAANVF SASGFKGFLL ELECDDNSSK GGLNSQLETI KGLLDEIKIT
DYKICSNNMK EGEMNFLCDL AYQYVKVLD
//
