ID A0A109UZN2_9SACH Unreviewed; 384 AA.
AC A0A109UZN2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=DNA damage checkpoint control protein RAD17 {ECO:0000256|PIRNR:PIRNR011769};
GN ORFNames=AW171_hschr42463 {ECO:0000313|EMBL:AMD20568.1};
OS Eremothecium sinecaudum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=45286 {ECO:0000313|EMBL:AMD20568.1, ECO:0000313|Proteomes:UP000243052};
RN [1] {ECO:0000313|EMBL:AMD20568.1, ECO:0000313|Proteomes:UP000243052}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58844 {ECO:0000313|EMBL:AMD20568.1,
RC ECO:0000313|Proteomes:UP000243052};
RA Dietrich F.S.;
RT "Genome sequence of the yeast Holleya sinecauda.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the checkpoint clamp complex involved in the
CC surveillance mechanism that allows the DNA repair pathways to act to
CC restore the integrity of the DNA prior to DNA synthesis or separation
CC of the replicated chromosomes. {ECO:0000256|PIRNR:PIRNR011769}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR011769}.
CC -!- SIMILARITY: Belongs to the rad1 family. {ECO:0000256|ARBA:ARBA00010991,
CC ECO:0000256|PIRNR:PIRNR011769}.
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DR EMBL; CP014244; AMD20568.1; -; Genomic_DNA.
DR RefSeq; XP_017987564.1; XM_018131858.1.
DR AlphaFoldDB; A0A109UZN2; -.
DR STRING; 45286.A0A109UZN2; -.
DR GeneID; 28723816; -.
DR OrthoDB; 2048785at2759; -.
DR Proteomes; UP000243052; Chromosome iv.
DR GO; GO:0030896; C:checkpoint clamp complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:UniProtKB-UniRule.
DR GO; GO:0006302; P:double-strand break repair; IEA:UniProtKB-UniRule.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR016587; Rad17.
DR InterPro; IPR003021; Rad1_Rec1_Rad17.
DR PANTHER; PTHR10870; CELL CYCLE CHECKPOINT PROTEIN RAD1; 1.
DR PANTHER; PTHR10870:SF0; CELL CYCLE CHECKPOINT PROTEIN RAD1; 1.
DR Pfam; PF02144; Rad1; 1.
DR PIRSF; PIRSF011769; Cell_cycle_RAD17; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|PIRNR:PIRNR011769};
KW DNA repair {ECO:0000256|PIRNR:PIRNR011769};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR011769};
KW Hydrolase {ECO:0000256|PIRNR:PIRNR011769};
KW Nuclease {ECO:0000256|PIRNR:PIRNR011769};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR011769}.
SQ SEQUENCE 384 AA; 43056 MW; 1EF9CACD9DB1219D CRC64;
MEQSSLFSAT SIHLDHITST LNCLMPFGQK DDVLVTIDKD GLSFVRENYH SSKIQLFLSK
DLFQHYCYNP AIDNPDAFTK LSIKINHIFE SLSIASNRSN DDIVECTLSH NGEGTPFILI
VEDSLITERA EYSTYFISDV DNTGLVLDRE SLEFECIIKG DVLYSALKDL KEIGCKECYL
YAMTSTRSRP IFALLSKSQL GFSKIMLPAE RSILEKLEVY NNDSKTIVHE SPVIGLFDFN
TIDKLRLSTK IASKALIRKD VHGLLTINIL SQANDMLIPN KIHSKADTSE QTVDYPSIFV
EVSVLEKATA LDTDIKDIQM LMSESTVQKP FSTTEQPMQS AFNAPTEQSK GNILGLTEPV
NFPSEQNAND SYNPVPTMDI PLFF
//
