ID A0A110B2Z0_9SPHI Unreviewed; 609 AA.
AC A0A110B2Z0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=protein-glutamate O-methyltransferase {ECO:0000256|ARBA:ARBA00012534};
DE EC=2.1.1.80 {ECO:0000256|ARBA:ARBA00012534};
GN Name=cheR {ECO:0000313|EMBL:BAU54038.1};
GN ORFNames=MgSA37_02209 {ECO:0000313|EMBL:BAU54038.1};
OS Mucilaginibacter gotjawali.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=1550579 {ECO:0000313|EMBL:BAU54038.1, ECO:0000313|Proteomes:UP000218263};
RN [1] {ECO:0000313|EMBL:BAU54038.1, ECO:0000313|Proteomes:UP000218263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA3-7 {ECO:0000313|EMBL:BAU54038.1,
RC ECO:0000313|Proteomes:UP000218263};
RA Lee J.S., Lee K.C., Kim K.K., Lee B.W.;
RT "Genome sequence of Mucilaginibacter gotjawali.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-
CC glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:24452, Rhea:RHEA-COMP:10208, Rhea:RHEA-COMP:10311,
CC ChEBI:CHEBI:29973, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:82795; EC=2.1.1.80;
CC Evidence={ECO:0000256|ARBA:ARBA00001541};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00050}.
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DR EMBL; AP017313; BAU54038.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A110B2Z0; -.
DR KEGG; mgot:MgSA37_02209; -.
DR OrthoDB; 9813151at2; -.
DR Proteomes; UP000218263; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0008984; F:protein-glutamate methylesterase activity; IEA:InterPro.
DR GO; GO:0008983; F:protein-glutamate O-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd16434; CheB-CheR_fusion; 1.
DR Gene3D; 1.10.155.10; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR Gene3D; 3.40.50.180; Methylesterase CheB, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR035909; CheB_C.
DR InterPro; IPR022642; CheR_C.
DR InterPro; IPR000780; CheR_MeTrfase.
DR InterPro; IPR022641; CheR_N.
DR InterPro; IPR036804; CheR_N_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR000673; Sig_transdc_resp-reg_Me-estase.
DR PANTHER; PTHR24422; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR PANTHER; PTHR24422:SF25; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR Pfam; PF01339; CheB_methylest; 1.
DR Pfam; PF01739; CheR; 1.
DR Pfam; PF03705; CheR_N; 1.
DR PRINTS; PR00996; CHERMTFRASE.
DR SMART; SM00138; MeTrc; 1.
DR SUPFAM; SSF47757; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR SUPFAM; SSF52738; Methylesterase CheB, C-terminal domain; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50122; CHEB; 1.
DR PROSITE; PS50123; CHER; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:BAU54038.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000218263};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:BAU54038.1}.
FT DOMAIN 25..214
FT /note="CheB-type methylesterase"
FT /evidence="ECO:0000259|PROSITE:PS50122"
FT DOMAIN 221..493
FT /note="CheR-type methyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50123"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 68252 MW; 321CDC92689A1AF6 CRC64;
MKKATNHTES KKMAASQPAD TSPHQQSAAF VVGIGASAGG LEALKILFDH MPPDSGMAFV
IVQHLDPTHR SMLTDLISPH TKMMVKEIIN GTTVKPDCVY VIPPDRELAI SEQRLFLAAM
PDERIKRRPI DSFFRSLAED LKENAIGIIL SGTGTEGTLG LKEIKAAGGL AIVQDPETAL
FDGMPRSAIT ARVADYIMPP GKIPEKLLDY INKKQNNDGR IVSGPPDLVE NDLKGIFQAI
RTQTGYDFTN YKTNTIARRI SKRIALNGFN AVEDYTKFLQ DHPNEITKLY KDFLIGVTSF
FRDKEVFNSF EKKAVPHLLE KCRDRQELRA WICGCSTGEE AYSLAIILKE ALEKNRQYLK
VTIFASDIDD EAIEFARNGI YNESALADVS PERLAQYFVK KENGYQPKKE IREMVVFAHH
NLIKDPPFSK MDLISCRNLL IYIKGDLQKK VIPVFHYSLN TDGLLLLGTS ESIGEHGDLF
TPIDAKHKIF KKKNINSRKP YPIFDLPFVE RKLDVKKQDM SSVVSKITRV SDIAEKLLAE
PSQPPSVIID MNNDALYFSG NTGIYLAPPD GVANWNILEM AKKGLRTVLE KAIKKHALPK
RPLKKIALR
//
