ID   A0A117I563_9MYCO        Unreviewed;      1333 AA.
AC   A0A117I563;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:GAS88037.1};
GN   ORFNames=RMCB_2133 {ECO:0000313|EMBL:GAS88037.1};
OS   Mycolicibacterium brisbanense.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=146020 {ECO:0000313|EMBL:GAS88037.1, ECO:0000313|Proteomes:UP000069620};
RN   [1] {ECO:0000313|EMBL:GAS88037.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM15654 {ECO:0000313|EMBL:GAS88037.1};
RA   Katahira K., Ogura Y., Gotoh Y., Hayashi T.;
RT   "Draft Genome Sequences of Five Rapidly Growing Mycobacterium Species, M.
RT   thermoresistibile, M. fortuitum subsp. acetamidolyticum, M. canariasense,
RT   M. brisbanense, and M. novocastrense.";
RL   Genome Announc. 4:e00322-16(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAS88037.1}.
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DR   EMBL; BCSX01000021; GAS88037.1; -; Genomic_DNA.
DR   STRING; 146020.RMCB_2133; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000069620; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000313|EMBL:GAS88037.1};
KW   Hydrolase {ECO:0000313|EMBL:GAS88037.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          90..253
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          312..478
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   COILED          800..827
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1333 AA;  147447 MW;  5F3D589A5610E4D9 CRC64;
     MTYITLGYTP ILGRVSQPSV AELRSRLDDL TIRDAARLGR RLKNLRGGDV PANLVEQFAA
     AEALVLTRQA AVPTITYPDL PVTSRRDEIA KAISENQVVI VAGATGSGKT TQLPKICLEL
     GRGIRGTIGH TQPRRLAART VAQRVADELG TPLGEAVGYT VRFTDQASDS TLVKLMTDGI
     LLAEIQRDRR LLRYDTLILD EAHERSLNID FLLGYLREQL PRRPDLKVIV TSATIEPERF
     SRHFGGAEHG CSGGAEHGCS GGAPIVEVSG RTYPVEIRYR PLEVPVVSDD DDDPDDPDHE
     IVRTEIRDPT EAIVDAVREL ESEPPGDVLV FLSGEREIRD TAEALKDLRN TEVLPLYARL
     PTADQQKVFQ PSHTGRRIVL ATNVAETSLT VPGIRYVVDP GTARISRYSR RTKVQRLPIE
     PISQASAAQR AGRSGRTAPG ICIRLYSEED FESRPRYTDP EILRTNLGAV ILQMAALGLG
     DIEKFPFLDA PDQRSIRDGV QLLQELGAFD SVGALTDVGR RLARLPLDPR VGRMILQADT
     EGCVREVLVL AAALSIPDPR ERPADKEEAA RQKHARFADE HSDFISYLNL WNYLREQRNQ
     LSGNAFRRMC REEFLHYLRV REWQDLVGQL RSIARDIGIR ESDEPAEPAA IHAALTAGLL
     SHIGLREGEP QARTRGPNWA QYAGARNSKF VLAPGSVLTK KPPRWIVVAD LVETSQLFGR
     IAARAEPEAI ERVAGHLVHR SYSEPHWEAR RGEVMAFERV TLYGLPLVPR RKVGYSSIEP
     DLARELFIRH ALVEGDWQTR HHFFRDNARL RAELEEIEER ARRRDLLVGD DDIYALYDAR
     IPADIVSARH FDAWWKKQRH RTPDLLTFTR DDLLRSEDGA DNPDTWQAGD LRLPLTYRFE
     PGAADDGVTV HVPVGVLARL GGDGFAWQVP ALREELVTAL IKSLPKDLRR NFVPAPDTAR
     AILGDIDASA ASLLDEVQRE LRRRSGILVP IDAFDLSKVP DHLRMTFAVE TADGKEVARG
     KDIDALREQL AVPVAQAVAD AVGGNLERTG LRAWPEDLDE LPRTVETASA GHTVRGYPAF
     VDTGKAVDIR VYATQAEQAA AMGPGLRRLL RLTVPSPVKA IERGLNPRVR LALNANPDGT
     LAALLEDCAD AAADVLLKRA VWTRAEFTAL AQQAAKELGP TTTAVVNRVQ SVLTAAHEVQ
     VALPDKPTPQ QADAVADIRA QLDRLLPKGF VTAAGAARLA DLARYVTAIA RRLDRLPQGI
     AADRERMARV HAVEDAYDDV IQALSAARAA DPKVAEIAWQ IEEFRVSLWA QQLGTPRPVS
     EQRIYKAINA IQN
//