ID A0A117IT92_9EURY Unreviewed; 435 AA.
AC A0A117IT92;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Glycosyl hydrolase family 4 C-terminal domain-containing protein {ECO:0000259|Pfam:PF11975};
GN ORFNames=APY94_09035 {ECO:0000313|EMBL:KUH32655.1};
OS Thermococcus celericrescens.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=227598 {ECO:0000313|EMBL:KUH32655.1, ECO:0000313|Proteomes:UP000053462};
RN [1] {ECO:0000313|EMBL:KUH32655.1, ECO:0000313|Proteomes:UP000053462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17994 {ECO:0000313|EMBL:KUH32655.1,
RC ECO:0000313|Proteomes:UP000053462};
RA Hong S.-J., Park C.-E., Shin J.-H.;
RT "Draft genome sequence of Thermococcus celericrescens strain DSM 17994.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 4 family.
CC {ECO:0000256|ARBA:ARBA00010141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUH32655.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LLYW01000031; KUH32655.1; -; Genomic_DNA.
DR RefSeq; WP_058939321.1; NZ_LLYW01000031.1.
DR AlphaFoldDB; A0A117IT92; -.
DR STRING; 227598.APY94_09035; -.
DR OrthoDB; 92947at2157; -.
DR Proteomes; UP000053462; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.90.110.10; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001088; Glyco_hydro_4.
DR InterPro; IPR022616; Glyco_hydro_4_C.
DR InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR32092; 6-PHOSPHO-BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF02056; Glyco_hydro_4; 1.
DR Pfam; PF11975; Glyco_hydro_4C; 1.
DR PRINTS; PR00732; GLHYDRLASE4.
DR SUPFAM; SSF56327; LDH C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 195..397
FT /note="Glycosyl hydrolase family 4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11975"
SQ SEQUENCE 435 AA; 49120 MW; 5C403C1D5EDCAB5D CRC64;
MRIAFIGAGS IFTPLGIYTI ATSEVLRNAE VYLVEIDDER RKFITALAEK MRKTFKAGFG
VTPLESVEGL EGHGLDYAVI SVEKERYERW KLDFKIPHRH GIRQVLGENG GLGGLAHTLR
VVPLVLEIAR RIEDINRDAG VFIYSNPEPR VTYAVLNYTG LKNVYGLCTG YLERKEMLAP
ILKADEREIS LIAGGLNHFT WIRELHVKGE DAYPRLDEAL KKRPDFEPLS QLLYRTYGLF
PSPDDNHIGE YLSFAWPLIP EEKKGLKWIE RTKKEGEEVR RLLRLFLRGL VPKFAFNRFV
KFPDVAMNVV EGLEGVEKLQ EAINVPNRGY IDLPKGTIVE VPAEVSPKGI KPLHVELPRE
ALVPLRVQAE IQRLSSEGAV EGNVEKVIKA VLLDPVVHDA EAGLRAMAEL MRAHLDALPQ
FDEGDIEILR LMAFS
//
