ID A0A117IUA8_9EURY Unreviewed; 310 AA.
AC A0A117IUA8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=5-formaminoimidazole-4-carboxamide-1-(Beta)-D-ribofuranosyl 5'-monophosphate synthetase {ECO:0000313|EMBL:KUH34333.1};
GN ORFNames=APY94_02415 {ECO:0000313|EMBL:KUH34333.1};
OS Thermococcus celericrescens.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=227598 {ECO:0000313|EMBL:KUH34333.1, ECO:0000313|Proteomes:UP000053462};
RN [1] {ECO:0000313|EMBL:KUH34333.1, ECO:0000313|Proteomes:UP000053462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17994 {ECO:0000313|EMBL:KUH34333.1,
RC ECO:0000313|Proteomes:UP000053462};
RA Hong S.-J., Park C.-E., Shin J.-H.;
RT "Draft genome sequence of Thermococcus celericrescens strain DSM 17994.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUH34333.1}.
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DR EMBL; LLYW01000007; KUH34333.1; -; Genomic_DNA.
DR RefSeq; WP_058938128.1; NZ_LLYW01000007.1.
DR AlphaFoldDB; A0A117IUA8; -.
DR STRING; 227598.APY94_02415; -.
DR OrthoDB; 98133at2157; -.
DR Proteomes; UP000053462; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016879; F:ligase activity, forming carbon-nitrogen bonds; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR023656; IMP_biosynth_PurP.
DR InterPro; IPR009720; IMP_biosynth_PurP_C.
DR InterPro; IPR010672; IMP_biosynth_PurP_N.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR PANTHER; PTHR38147:SF2; 5-FORMAMINOIMIDAZOLE-4-CARBOXAMIDE-1-(BETA)-D-RIBOFURANOSYL 5'-MONOPHOSPHATE SYNTHETASE; 1.
DR PANTHER; PTHR38147; 5-FORMAMINOIMIDAZOLE-4-CARBOXAMIDE-1-(BETA)-D-RIBOFURANOSYL 5'-MONOPHOSPHATE SYNTHETASE-RELATED; 1.
DR Pfam; PF06849; DUF1246; 1.
DR Pfam; PF06973; DUF1297; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
PE 4: Predicted;
FT DOMAIN 3..114
FT /note="IMP biosynthesis enzyme PurP N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06849"
FT DOMAIN 158..310
FT /note="IMP biosynthesis enzyme PurP C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06973"
SQ SEQUENCE 310 AA; 35388 MW; 53C75EB6AB7E8146 CRC64;
MIISTIASHS SLQILMGAKR EGFRTRLYVK PNRKAFYSSI PPVDEIVVTE NMREVLGDDG
IVVPHGSFVA YLGIEAIEKA NTKFFGNKRF LKWETSFELQ DRVLKKAGIP TVEVIEPEEA
KPDELYFVRL EGPRGGSGHF LAYGYELEEK IKGLSEPYRI ERFTDGVYLY VHFFYSPILN
RLELFGVDER LVIADANKRR PFRTLPYTIA GNKAVALRES LIPVLYDYGL AFVKAMEELE
PPGIIGPFAL HFAYDGEFRC IGFASRIDGG SNAKHWYSAL YWERPMLMGE RIAREIKLAL
EEDRLEEVVT
//
