ID A0A117JPY8_9MYCO Unreviewed; 794 AA.
AC A0A117JPY8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Molybdopterin oxidoreductase {ECO:0000313|EMBL:KUI25413.1};
GN ORFNames=AU194_00475 {ECO:0000313|EMBL:KUI25413.1};
OS Mycobacterium sp. GA-2829.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1772283 {ECO:0000313|EMBL:KUI25413.1, ECO:0000313|Proteomes:UP000053444};
RN [1] {ECO:0000313|EMBL:KUI25413.1, ECO:0000313|Proteomes:UP000053444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GA-2829 {ECO:0000313|EMBL:KUI25413.1,
RC ECO:0000313|Proteomes:UP000053444};
RG TB Trials Study Group;
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E.L., Macaden R.,
RA Grewal H.M.S.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUI25413.1}.
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DR EMBL; LQIT01000056; KUI25413.1; -; Genomic_DNA.
DR RefSeq; WP_059092177.1; NZ_LQIT01000056.1.
DR AlphaFoldDB; A0A117JPY8; -.
DR STRING; 1772283.AU194_00475; -.
DR OrthoDB; 7376058at2; -.
DR Proteomes; UP000053444; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053444}.
FT DOMAIN 38..94
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 794 AA; 87138 MW; 7058F93DB7B0AAE3 CRC64;
MADRITEPWG ARTPYGRGER WPHRVDAHLA DGLDEDAVGW VQSASVLHSN GDGLDIAVHD
GRIAGVRGRR NDRVNHGRLD PKDMFGWQAN NSADRLTTPL IRVGGELVET DWDTAMERIV
ARSRTLLDTF GPSSIGFYTS GQLFLEEYYT QAVVAHGAIG TNHVDGNTRL CTATAAEALK
ESFGCDGQPG SYTDVDHADV IALYGHNVAE TQTVLWMRML DRLAGPNPPR IVCVDPRLTP
VARHATVHLA PLPGTNVALM NGLLHELIRN DWVDQDYIDA HTVGFEELDK RVAEFPLQRV
AEICRVPAAR VGEAAEVIGT ATALLSTVLQ GFYQSHQATA AAVQVNNIHL VRGMLGRPGC
GLLQMNGQPT AENTRECGAD GDLAGFRNWA NDSHVEDLAR LWHIETRQIP HYAPPTHVMQ
MMRYAEQGTL RMLWVSATNP AVSLPELDRI RAILADERLF LVVQDIFRTE TAELADVVLP
AAAWGEKVGT FTNADRTVHL SEHAVDPPGD ARPDLDILLD YARRMDFRDA DGEPLPPWTD
AESAFEAWKQ CSAGRPCDYT GLTYARLRGS GGIQWPCTAE HPEGTERLYA DGRFWAHPDY
CEAYGKDLVT GAPLEPTEYR AMNPHGRAII KAAEYLEPHE PPGDTYPFVL ITGRTLYHFH
TRTKTARAPE LQAAAPQPWV EMSPADARRG GIAEGDVVRV VTPRGSVTAA CRISGIRDGV
VFVPFHYGYW DVPQIPESDG HHRAANELTL TDWDPVSKQP IFKTAAARVH WVRAGTGPAP
APTLTASAPA GEAT
//
