ID A0A117KCX8_9ACTN Unreviewed; 383 AA.
AC A0A117KCX8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:KUJ58214.1};
GN ORFNames=ADL25_04340 {ECO:0000313|EMBL:KUJ58214.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ58214.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ58214.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMWH01000015; KUJ58214.1; -; Genomic_DNA.
DR RefSeq; WP_059126332.1; NZ_LMWH01000015.1.
DR AlphaFoldDB; A0A117KCX8; -.
DR OrthoDB; 241504at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08282; PFDH_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054048}.
FT DOMAIN 8..375
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 383 AA; 40810 MW; 8252151827677493 CRC64;
MKAVVYEKPF SVAVRDVDDP QMQHPNDVLV RVTSTAICGS DLHMYEGRTA AEPGIVFGHE
NLGIVEEIGS GVTSLAKGDR VVMPFNVACG FCKNCLAGET GFCLTVNPGF AGGAYGYVAM
GPYEGGQAEL LRVPFADFNC LKLPPGEQFE TDFVLLADIF PTGYHGCELA QVSPGESVAV
YGAGPVGLMA AYSALLRGAS KVFCVDRVPE RLAKAKEIGA IPIDFTKGDA AEQIKEQTHG
EGTDKGVDAV GYQAQAHDAS HEEPAVVLNA LVETVRPTGR LGVPGLYVPS DPGAPDEHAK
HGQLLVSIGK MFEKGQKMGT GQCNVKRYNR QLRDLIIAGR AKPSFVVSHE LPLDQAPLAY
EKFDKRVEGY TKVVLHPGHA LAA
//
