ID A0A117MMS4_9ACTN Unreviewed; 680 AA.
AC A0A117MMS4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Flagellar biosynthesis protein FlhA {ECO:0000313|EMBL:KUL25975.1};
GN Name=flhA {ECO:0000313|EMBL:KUL25975.1};
GN ORFNames=ADL15_39245 {ECO:0000313|EMBL:KUL25975.1};
OS Actinoplanes awajinensis subsp. mycoplanecinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL25975.1, ECO:0000313|Proteomes:UP000053244};
RN [1] {ECO:0000313|EMBL:KUL25975.1, ECO:0000313|Proteomes:UP000053244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL25975.1,
RC ECO:0000313|Proteomes:UP000053244};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL25975.1}.
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DR EMBL; LLZH01000309; KUL25975.1; -; Genomic_DNA.
DR RefSeq; WP_067702685.1; NZ_LLZH01000309.1.
DR AlphaFoldDB; A0A117MMS4; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000053244; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000313|EMBL:KUL25975.1};
KW Cilium {ECO:0000313|EMBL:KUL25975.1};
KW Flagellum {ECO:0000313|EMBL:KUL25975.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053244};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 680 AA; 71621 MW; 153F142CB4029FDD CRC64;
MKKPSISRLA VPIGVIGIII MMVVPLPTFL LDLLIAFNIT VALLVLLTSM FVEKPLDFAV
FPALLLVMTL FRLALNISAT RLVLRDGDAG KVIHAFGSFV VGGNLVIGLV IFSILVIVQM
IVVTKGAERV AEVGARFTLD AMPGKQMAID ADLNAGLIDE SAAKKRRAEV AAEAEFYGAM
DGGSKFVKGD AVAAIIITLI NLIGGFAVGI LQHGLSPTDS MNQFSMLSIG DGLVSQVPAL
LLSVATGLIV TRSATSGDMG QSVTAQLGQN KLALRIGGAA ALALCVIPGL PKIPFLVVGV
AVLVIAQRVK ETVPDEDLPV VEAVEMPAAD SPEQLLGEMR IDPLELALAP DLVDLVDVNS
GDLLDRVRAL RRKMALELGV IMPPVRTRDD LDLPLSSYAI RISGVDAGTG QAPPGTVLAI
GEGLQALPGR AGVEPVFGLA GKWVPAELHY QAELSGATVV DRASVIITHL AEVVRNNASR
LLGREDVRAL SEMVKRTHPV VVEELTPGLL SLGQIQKVLQ AMLDEGVPIR DLVRIFESLS
LRAKLSQDHD GLIEAARNAL GPAIAAQYAT AGRLTVITLD PMLEQSLLES LRPSETGAFM
AIDGMRAEAI VSEASRLAEA AEQQGLNPVL ACSPQLRLPL MRLLRAGSRR VQVLSYSEIS
GSTAQIETIG VVNGAYAGAA
//
