ID   A0A117PAN2_9ACTN        Unreviewed;       518 AA.
AC   A0A117PAN2;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=AQI70_15880 {ECO:0000313|EMBL:KUM76135.1};
OS   Streptomyces curacoi.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=146536 {ECO:0000313|EMBL:KUM76135.1, ECO:0000313|Proteomes:UP000054024};
RN   [1] {ECO:0000313|EMBL:KUM76135.1, ECO:0000313|Proteomes:UP000054024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40107 {ECO:0000313|EMBL:KUM76135.1,
RC   ECO:0000313|Proteomes:UP000054024};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces curacoi DSM 40107, type strain for
RT   the species Streptomyces curacoi.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM76135.1}.
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DR   EMBL; LMWJ01000010; KUM76135.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A117PAN2; -.
DR   STRING; 146536.AQI70_15880; -.
DR   ESTHER; strvr-l8pq07; Carb_B_Bacteria.
DR   OrthoDB; 3199405at2; -.
DR   Proteomes; UP000054024; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR   PANTHER; PTHR43142:SF1; CARBOXYLIC ESTER HYDROLASE; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054024}.
FT   DOMAIN          2..448
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   518 AA;  55442 MW;  0DB0F77736B63056 CRC64;
     MVSTPYGSVR GRYEHGVAVF RGIPYAAPPF GPHRFRPPVP PEPWDGVRDA VAFGPTAPKP
     PYSEAFAQYL SDPVVPGDDC LNLNVWTPEP GPGARLPVMV FLHGGALTRG SSGVPVYDGR
     PFARDGVVLV SVNYRLGVEG YGLFPDAPAN AGLRDQLAAL EWVHESIAAF GGDPGRITLF
     GQSAGAISVG ALLAAPQARG LVRRAILQSG PPEAAEWDKV RRMVRRMATR LRIPATAAAF
     ADVDRELLLR TQADVGRLSS PVVGGPAFGI VVDGDIVPRD PLEALTEGDA SSGVDLMMGW
     TRDEYRLWLV PGGLLERVDR LGAVALAGAM ARCHVGADVP RGYRALHPEA GTAELVGQMV
     TDHLLRVPLH RLADARPGAS YVYEFAWPSN LPYLGACHAL ELGFVFDTGE VPESRKLAGE
     GAPQELADEM HRAWLRFAVE GDPGWQAWDD THPVRVFGDG ATHTAYGPRD AELALWAAAV
     RVAESTPASV LADGSPTRGT EPRSAVRRLR LPGAVRRH
//