ID   A0A117PCB3_9ACTN        Unreviewed;       948 AA.
AC   A0A117PCB3;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Acyl-CoA synthetase {ECO:0000313|EMBL:KUM77066.1};
GN   ORFNames=AQI70_14110 {ECO:0000313|EMBL:KUM77066.1};
OS   Streptomyces curacoi.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=146536 {ECO:0000313|EMBL:KUM77066.1, ECO:0000313|Proteomes:UP000054024};
RN   [1] {ECO:0000313|EMBL:KUM77066.1, ECO:0000313|Proteomes:UP000054024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40107 {ECO:0000313|EMBL:KUM77066.1,
RC   ECO:0000313|Proteomes:UP000054024};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces curacoi DSM 40107, type strain for
RT   the species Streptomyces curacoi.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM77066.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LMWJ01000008; KUM77066.1; -; Genomic_DNA.
DR   RefSeq; WP_062148634.1; NZ_KQ947987.1.
DR   AlphaFoldDB; A0A117PCB3; -.
DR   STRING; 146536.AQI70_14110; -.
DR   OrthoDB; 190266at2; -.
DR   Proteomes; UP000054024; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR42793; COA BINDING DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR42793:SF1; PEPTIDYL-LYSINE N-ACETYLTRANSFERASE PATZ; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   Pfam; PF13549; ATP-grasp_5; 1.
DR   Pfam; PF13380; CoA_binding_2; 1.
DR   Pfam; PF13607; Succ_CoA_lig; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054024}.
FT   DOMAIN          26..185
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
FT   REGION          630..659
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        645..659
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   948 AA;  100551 MW;  50C84431B871F777 CRC64;
     MQTSSDRHEY PAHWEADVVL RDGGTARIRP ITVDDAERLV SFYEQVSDES KYYRFFAPYP
     RLSAKDVHRF THHDFVDRVG LAATVGGEFI ATVRYDRIGA DGMPASAPAD EAEVAFLVQD
     AHQGRGVASA LLEHIAAVAR ERGIRRFAAE VLPANTKMIK VFTDAGYTQK RSFEDGVVRL
     EFDLEPTDRS LAVQYAREQR AEARSVQRLL VPGSVAVIGT GRSPGGVGRG VLGNIRDAGF
     TGRLYAVNRA FPDDLKELDG VPAHRSVRDI DGPVDLAVVA VPAAYVPEVV AECGEHGVQG
     LVVLSAGYAE SGPDGRERQR ALVRQARAYG MRIIGPNAFG IINTSASVRL NASLAPEMPR
     PGRIGLFAQS GAIGIALLSR LHRRGGGVTG VTGVSTFVSS GNRADVSGND VLQYWYDDPD
     TDVVLMYLES IGNPRKFTRL ARRTAAAKPL VVVQGARHGG AAPQGHAVRA TRLPHATVSA
     LLRQAGVIRV DTITELVDAG LLLARQPLPA GPRVAILGNS ESLGLLTYDA CLSEGLRPLP
     PLDLTTGASA ADFHAALSRA LADETCDAVV VTAIPAIGDA STGDAELAQA LRSAAERVPG
     KPVLVVHVEL GGLAEALSAA ASTAPQAVTT APGLASRAHP FRPLDFPADP QPGQPDPAED
     APRLIPAYPA AERAVRALAE AVNYSQWRRE AADPGKVPEY EDIDERGAAR LIDGLLARGQ
     GLTLGTDETC DLLGKYGIQV HRALHAPTPD AAADAARALG YPVALKATAP HLRHRADLGG
     VRLDLADEEQ LRRAYAELTD LFGKPEELRP VVQGMAPRGV DTVVRAVIDP AAGAVLSFGL
     AGAASQLLGD MAHRLIPVTD REATSIVRSI RTAPLLFGWR GSAPVDTPAL EELLLRMSRL
     VDDHPEVVAV TLEPVVVATH GLSVLGASVR LAPPPARDDL GPRTLPTY
//