ID A0A117PER4_9ACTN Unreviewed; 1157 AA.
AC A0A117PER4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:KUM78276.1};
GN ORFNames=AQI70_12400 {ECO:0000313|EMBL:KUM78276.1};
OS Streptomyces curacoi.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=146536 {ECO:0000313|EMBL:KUM78276.1, ECO:0000313|Proteomes:UP000054024};
RN [1] {ECO:0000313|EMBL:KUM78276.1, ECO:0000313|Proteomes:UP000054024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40107 {ECO:0000313|EMBL:KUM78276.1,
RC ECO:0000313|Proteomes:UP000054024};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces curacoi DSM 40107, type strain for
RT the species Streptomyces curacoi.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM78276.1}.
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DR EMBL; LMWJ01000007; KUM78276.1; -; Genomic_DNA.
DR RefSeq; WP_062147614.1; NZ_KQ947986.1.
DR AlphaFoldDB; A0A117PER4; -.
DR STRING; 146536.AQI70_12400; -.
DR OrthoDB; 9759518at2; -.
DR Proteomes; UP000054024; Unassembled WGS sequence.
DR GO; GO:0009325; C:nitrate reductase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0008940; F:nitrate reductase activity; IEA:InterPro.
DR GO; GO:0042126; P:nitrate metabolic process; IEA:InterPro.
DR CDD; cd02776; MopB_CT_Nitrate-R-NarG-like; 1.
DR Gene3D; 3.40.50.12440; -; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037943; MopB_CT_Nitrate-R-NarG-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR InterPro; IPR006468; NarG.
DR NCBIfam; TIGR01580; narG; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR PANTHER; PTHR43105:SF2; RESPIRATORY NITRATE REDUCTASE 2 ALPHA CHAIN; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054024}.
FT DOMAIN 49..760
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 1014..1092
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
FT REGION 781..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1157 AA; 126082 MW; 3DB1F6603B450314 CRC64;
MTDTQIPPAA PAEPGAALLE AGRFFRPGTP APDAHGVAAF SWYACSPTRV RHPYVRGVLL
EMYWEAKERL RDPVLAWADV QSDPERRRRY QRARGKGGLV RASWDEATEL VAAAQVHTIK
TYGPDRVAGF FAAPAMSMVS HAAGARFHAL IGAPMLSFHD GYADLPVASP QVLGDQADVP
ESGDWWDAAH LLLWGSDVPV TRTPDAHWLA EARYRGQKVV AVGPDHAGHA SFADEWLHPH
PGTDGALALA MGHVILKEFF VDRETPFFAD YVQKFTDLPF LVTLAERDGA YVPAKFLRAS
DLGPEGEGAE WKTVVLDEVA GRAVVPNGSL GFRWTASGKG RWNLELGATR PRLSLYGSED
AAGVEVLLPR FDTEGGAPGQ GRGAVVRRGV PAMKAGGARG PLVTTVFDLL LAQYGVARDG
LPGRWPASYD DADAPGTPAW QEAHTSVPAA TCVRIAREFA RTAEQSAGRC MILTGTGTTH
WFHSETIHRA VLALLQLTGC QGRNGGGWAH YGGREKCRPM TGWATLATAS DWSRPPRRMT
GTAYWYLHTD QWRHDLCTAD VLASPLGAGR FRGMTGADCL ALSVRSGWMP SYPTFDRSPL
ELGEVFGDPV ARVVAELRAG TLKFACEDPD APENWPRVLT LWRADLFGSP EKGADHFARH
LLGTHSSPRA EEAPEEVRPR DVAWRDEAPE GKLDLLLSLD FRQTPSTLVS DVVLPAATRY
EKHDLSSTDL HPCVDSCAPA VDPPGQPRTD FDTFKALAER LSEQAVGHLG VRKDLVASPL
QHDTPGEIAQ PGGVASDWKR GECDPVPGRT MPDLTVVERD YTAIGAQFSA LGPLVERLGL
STKGITLLPD EEVEDLRLLN GVTDDGRPRL DTAIKAANTI LALSGATNGR LATQGFRALD
ARTGQETAHL TDEHEGKRIT YADTQAAPVP VITSPERSGS EADGRRYAAF TLNTEHGKPW
HTLTGRQHFF LDHDWIHELG EALPVYRPPL DLHKLLGEPR RGPDGQPEVT VRHLTPHDKW
SLHCEYQDDL FMLALSHGGQ HLWMSPRDAE AIGVADNAWV EAVDRNGVIV ARAVVSHRIP
PGTVYTHRAQ ERTAAGPKAE TAGRHGGLRY SPARLILKPS HLVGGYAQLS WAFNYLGPTG
NQRDEVTVIR RRSQEVD
//
