ID A0A117PPW0_9ACTN Unreviewed; 789 AA.
AC A0A117PPW0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=beta-mannosidase {ECO:0000256|ARBA:ARBA00012754};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
GN ORFNames=AQI94_25515 {ECO:0000313|EMBL:KUM85237.1};
OS Streptomyces pseudovenezuelae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=67350 {ECO:0000313|EMBL:KUM85237.1, ECO:0000313|Proteomes:UP000053039};
RN [1] {ECO:0000313|EMBL:KUM85237.1, ECO:0000313|Proteomes:UP000053039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40212 {ECO:0000313|EMBL:KUM85237.1,
RC ECO:0000313|Proteomes:UP000053039};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces pseudovenezuelae DSM 40212, type
RT strain for the species Streptomyces pseudovenezuelae.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM85237.1}.
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DR EMBL; LMWM01000029; KUM85237.1; -; Genomic_DNA.
DR RefSeq; WP_031044874.1; NZ_KQ948149.1.
DR AlphaFoldDB; A0A117PPW0; -.
DR OrthoDB; 9758603at2; -.
DR Proteomes; UP000053039; Unassembled WGS sequence.
DR GO; GO:0004567; F:beta-mannosidase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 229..277
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
SQ SEQUENCE 789 AA; 88697 MW; 60A526195B946C15 CRC64;
MLQATPLTDG WILRHEGGAL PAVVPGCVHT DLLAAGLIPD PFLGRNESDL AWVGRREWTY
ERDLAPVNGH EQTDLVFDGL DTVAEVLLDG RLLGRTRNMH RSYRFDVTGM SGRLTVRFVS
AYAEAEAVRG KLGERPAAYA EPYQYLRKMA CSFGWDWGPT LVTAGIWRPV RLERWSTARI
AWVRPLVTVE QGVGVVELAV EVERARVEAP LTVEATVGGV RVRAALDGTS GTVRLRVPDV
RLWWPRGYGE QPLYEVELTL LHEDRPLDVW RRRVGFRTVE LDRSADEHGS GFTFVLNGER
LFARGVNWIP DDVFPSRITR ERYRERLGQA AEAGVDLVRI WGGGIYESED FYDACDELGL
LVWQDFPFAC AAYPEEQPLR GEVEAEAREN VVRLMPHPSL VLWNGNNENL WGFRDWDWEA
RLAGDSWGEG YYLGVLPRVV AESDPTRPYT AGSPWSGSWA HHPNDPAHGT HHSWEVWNRL
DYAGYRDDVP RFVAEFGWQA PPAYATLARA LPGEELAADS PGVLHHQKAD DGNGKLRRGL
ERHFAFPEGD FDRWHYLMQV NQARAVAAGI EHWRSRWPVC AGTVLWQLND CWPVTSWAAV
DGDGREKPLY HELRRLYADR LLTVQERAQG LVLAAVNQAG DPWAGVLRLR RMSVDGEVLG
ETGVDFGTER RAVAHVDVPR ELEPVGPKEF LVVDVDGLRA LHFPAPDREI PYPRAEFDVT
VAPGAVTVTA RTLVRDLLLQ ADRLHPDARA DRGLLTLLPG ERVTIGVRGW ETPDADAARS
ALYFLEPSR
//
