ID A0A117R253_9ACTN Unreviewed; 339 AA.
AC A0A117R253;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:KUN66886.1};
GN ORFNames=AQJ54_16945 {ECO:0000313|EMBL:KUN66886.1};
OS Streptomyces griseorubiginosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67304 {ECO:0000313|EMBL:KUN66886.1, ECO:0000313|Proteomes:UP000054375};
RN [1] {ECO:0000313|EMBL:KUN66886.1, ECO:0000313|Proteomes:UP000054375}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40469 {ECO:0000313|EMBL:KUN66886.1,
RC ECO:0000313|Proteomes:UP000054375};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces griseorubiginosus DSM 40469, type
RT strain for the species Streptomyces griseorubiginosus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN66886.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMWV01000014; KUN66886.1; -; Genomic_DNA.
DR RefSeq; WP_062238200.1; NZ_KQ948736.1.
DR AlphaFoldDB; A0A117R253; -.
DR Proteomes; UP000054375; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR21708:SF42; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054375}.
FT DOMAIN 4..157
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 188..309
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 339 AA; 35424 MW; E22A0FAD1ECD3D5E CRC64;
MRYIIIGAGA VGGVVGGRLA GGGCEVVLVA RGAQYAALRD GGLRLRVPDG EFTHRLPVVD
GPAGLGTLRA DDALVLAVKT QDTQAALDAW GPAPVAGGGT AAGRLPLLCA QNGVEGQRMA
LRTFRHVYGV CVWLPATFVE PGVVSAAGSP LTGILHLGRY PRGTDETVRL IADDLEKARF
EAPVVPDLSR WQYAKLLANL ANAVEAVTGP VEGEAALEFV ERVRAEGTAV LDAAGIAYTS
PEEQRARRGD KVTLVPLANA PRGGGSSWQS LVRGTGTVEA DYLNGEIALL GRLHGVPTPL
NELLQHLANT FARERREAGS MPLSELVRLA DEAEAAVAE
//
