ID   A0A117S1X0_9ACTN        Unreviewed;       723 AA.
AC   A0A117S1X0;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   ORFNames=AQJ91_06575 {ECO:0000313|EMBL:KUO21801.1};
OS   Streptomyces dysideae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=909626 {ECO:0000313|EMBL:KUO21801.1, ECO:0000313|Proteomes:UP000053260};
RN   [1] {ECO:0000313|EMBL:KUO21801.1, ECO:0000313|Proteomes:UP000053260}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RV15 {ECO:0000313|EMBL:KUO21801.1,
RC   ECO:0000313|Proteomes:UP000053260};
RA   Ruckert C., Abdelmohsen U.R., Winkler A., Hentschel U., Kalinowski J.,
RA   Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces sp. RV15, isolated from a marine
RT   sponge.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO21801.1}.
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DR   EMBL; LMXB01000021; KUO21801.1; -; Genomic_DNA.
DR   RefSeq; WP_067017378.1; NZ_KQ949077.1.
DR   AlphaFoldDB; A0A117S1X0; -.
DR   STRING; 909626.AQJ91_06575; -.
DR   Proteomes; UP000053260; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR031634; PknG_rubred.
DR   InterPro; IPR031636; PknG_TPR.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF16919; PknG_rubred; 1.
DR   Pfam; PF16918; PknG_TPR; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Kinase {ECO:0000256|ARBA:ARBA00022527};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053260};
KW   Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          139..401
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          21..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          694..723
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         168
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   723 AA;  77777 MW;  E44C80A8A7EAB1E4 CRC64;
     MCNRPDCGRG EIDEQGFCDV CDREPLPADR AGPAARAPQP ARAPQPARGP SVGVAHVRPD
     PWYGLGLVDS DQAPEAADVP RRSADPVPEE HRYCANPSCM QPVGRGHDGE PGRTTGFCPH
     CGTGFDFSQP GGRTIAGRYD LQLVLGSGAY GAAFLAHDRN LATDVVLKAL NKSVARTALH
     ERDVLVGLRH DSIVRILGYE RQGPHLVLEY VPGVPLSARD GDRLETLLAH GVRVLQALDY
     LHARGLLHCD VKPLNIIRFR EESPAGALDR VRLIDFGAVR SQKDTGRIVA CTPAYAPPED
     DPDHLRPAPG FDLYGLGMTL REVCRSRWTD RSAPGVDSLH LLLDRATDVE RPWRRFVSAR
     QFAEQLSGVI RQVVAGPPAH RQVARPSALF GSMPEPLHGG LGAARPLAHW VGAEPDEDGT
     LTLRAAFSSP EPGDIAAALP VPLSDPDDPG MAGSAGTALA ECRLALRRKD SAQAERTLSA
     AGLPNWHWLH AWYSGLIALA RADAPRAAAE FIQVRTALPG ELIPQLALGL CAELRGDHAA
     ARSYYGAVFD TTPALGAAGF GLARVHVLAG ERAKAVATAE RLAQEFRYER EARVAAVRLR
     AMVLGGPSSH PAPTEDDLER AGASLVGLSV DRAAAAGLRA EIRYAKFLRD HDRVKLSDAI
     RELAPHAPTE REYVALVDLA NRLRPPLRWR WSGRRGRTGH SRFGETPGTL SSDTPSGGRG
     HAP
//