ID A0A117SKV0_9FIRM Unreviewed; 811 AA.
AC A0A117SKV0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC {ECO:0000313|EMBL:KUO77073.1};
GN ORFNames=APF77_23560 {ECO:0000313|EMBL:KUO77073.1};
OS Clostridia bacterium BRH_c25.
OC Bacteria; Bacillota; Clostridia.
OX NCBI_TaxID=1734399 {ECO:0000313|EMBL:KUO77073.1, ECO:0000313|Proteomes:UP000057710};
RN [1] {ECO:0000313|EMBL:KUO77073.1, ECO:0000313|Proteomes:UP000057710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRH_c25 {ECO:0000313|EMBL:KUO77073.1};
RA Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT "Microbial metabolic network in the subsurface.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO77073.1}.
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DR EMBL; LOES01000023; KUO77073.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A117SKV0; -.
DR STRING; 1734399.APF77_23560; -.
DR Proteomes; UP000057710; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:KUO77073.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:KUO77073.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 4..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 420..455
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 416..462
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 811 AA; 90039 MW; BC560FD44978B4EC CRC64;
MGVFDKFTER AQKVMVYSQE EALRLSHSYI GTEHILLGLI REGEGIAAQV LKNKGIAFDT
VKQQIEAVIG KGEQEVEQVM GYTPRTKTVL ELSVDEARSL GHGYIGTEHL LLALIREGEG
VAAQILVAMG LNFDAVRQEI MSLLNNEGAK SKPGAAPAKG AKTPALNQFG RDLTEMAKEG
KLDPIIGREK EIERMIQILS RRTKNNPVLI GDPGVGKTAI AEGLAQKIIE GNIPEILRGK
RVITLDLSSM VAGSKYRGEF EERLKNVMNE IRESKNVILF IDEMHTIIGA GGAEGAIDAS
NILKPALARG EIQAIGATTL DEYRKHVEKD PALERRFQPV TVGEPTKEEA LLILQGLRDK
YEAHHKVKIT DEAIKAAVDL SDRYIADRFL PDKAIDLVDE AASKVRIKIF TAPPDHKKLE
DDLAALDKEK AEAISLQNYE RAAQIRDSIQ SMKQQLEDSK KSWNDKTTSK DSVVTEEDIA
AIVSSWTGVP VTKLAEEESR RLLNLESILH ERVIGQEEAV LAVSKAIRRA RVGLKDPKRP
VGSFIFLGPT GVGKTELSKA LAEALFGDEN AVIRIDMSEY MEKHTVSKLI GSPPGYVGYE
EGGQLTEKVR RKPYSVILLD EIEKAHPDVF NVLLQILDDG RLTDGKGRTV DFKNTVVIMT
SNVGISMIKK QAVLGFATST NEREDAYEKM KGNIMEELKR TFRPEFLNRV DEIIVFHQLE
EEHLKQIVEM MLKSLLGRVS EMNINVEVTD KAKALLVEKG YDQAYGARPL RRAIQKMVED
QLSEEMLKGD IKQGSDILID AEDDKLVFGN K
//
