ID A0A119A8C1_9FLAO Unreviewed; 804 AA.
AC A0A119A8C1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Multidrug-efflux transporter MexB {ECO:0000313|EMBL:KVV13198.1};
GN Name=mexB {ECO:0000313|EMBL:KVV13198.1};
GN ORFNames=AP058_02560 {ECO:0000313|EMBL:KVV13198.1};
OS Flavobacterium sp. TAB 87.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1729581 {ECO:0000313|EMBL:KVV13198.1, ECO:0000313|Proteomes:UP000059935};
RN [1] {ECO:0000313|EMBL:KVV13198.1, ECO:0000313|Proteomes:UP000059935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAB87 {ECO:0000313|EMBL:KVV13198.1,
RC ECO:0000313|Proteomes:UP000059935};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVV13198.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LLWK01000038; KVV13198.1; -; Genomic_DNA.
DR RefSeq; WP_066311410.1; NZ_LLWK01000038.1.
DR AlphaFoldDB; A0A119A8C1; -.
DR STRING; 1729581.AP058_02560; -.
DR PATRIC; fig|1729581.3.peg.2643; -.
DR OrthoDB; 9805018at2; -.
DR Proteomes; UP000059935; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000059935};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 615..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..668
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 674..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 715..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 745..766
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 256..381
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 644..772
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 804 AA; 90983 MW; 26B6D39580451A2A CRC64;
MKKKLKVGFW EFIARIVLKN RIAILSLIIL LTVFFGLQWK NIQFSFTEAN LLPDDHPINN
EYNTFLKEFG EEGNLIVVGV KDDAFYTPKA FEAWGKLMAS IKAQKEVDLI VSISDLQKLQ
KNDSLQTFEL VPFVNQSKTK DKTYLTSLKK DLFEKMPFYE GLLFNKKSGS IRSAIYLDKK
IVNTERRKDY ILNDFIPKIE AFEEETGIDL RVSGMPYIRT LNAKSITDEI SLFVGASLLI
TSLIFFFFFR SFRATLISMV IVIIGVMWTF GFLGLFHYEI TVLTALVPSL VIVIGIPNCI
FLTNKYQQEY QAHGNKAKAL QRVITKVGTA TLMTNLTTAA GFATFIITNS VLLKEFGIVA
SVSIVSLFFL CLITIPIYYS YQPIPKERHL EHLSRNYTRA FMEWIEHTVR YKRRYVYGVA
ILIFAVGIFG ALQIKTSGSL IEDMPQKTGF FNDILFFEQE FDGIMPLEIT IDTERKKGAM
KLSNLKKMDE LQSAIEEIPE LSKPISILNL VKYSKQAYYN GNPDYYALPT AQEQSFILSY
AKNTSKNADE NVMKSYVDST GQIARITTFM KDIGTGNMAK IEDKLQSKID SIFPADHYKV
VLTGKAFVFE KGTKYLLSNL VTSLLFAVLL ISLLMVFMFR SLKMVVVSLI PNLLPLMITA
GLMGYFGIPL KPSTILVFSI AFGLSVDDTI HFLAQYRQEL TKNNWKIKRS VYATLKEAGV
SMFYTSVVLF AGFSVFMLSD FGGTVALGGL IAITLGFGML SNLILLPSLV LTLNKKLANQ
QEFTKPTIDV LADLSETEDE RNER
//
