ID A0A119UQD1_9BURK Unreviewed; 537 AA.
AC A0A119UQD1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=2,3-dihydroxybenzoate-AMP ligase {ECO:0000313|EMBL:KWK69204.1};
GN Name=entE {ECO:0000313|EMBL:KWK69204.1};
GN ORFNames=WM16_24040 {ECO:0000313|EMBL:KWK69204.1};
OS Burkholderia ubonensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=101571 {ECO:0000313|EMBL:KWK69204.1, ECO:0000313|Proteomes:UP000065504};
RN [1] {ECO:0000313|EMBL:KWK69204.1, ECO:0000313|Proteomes:UP000065504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSMB782WGS {ECO:0000313|EMBL:KWK69204.1,
RC ECO:0000313|Proteomes:UP000065504};
RA Sahl J., Keim P., Wagner D.;
RT "Expanding the genomic diversity of Burkholderia species for the
RT development of highly accurate diagnostics.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWK69204.1}.
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DR EMBL; LPLU01000111; KWK69204.1; -; Genomic_DNA.
DR RefSeq; WP_060237519.1; NZ_LPLU01000111.1.
DR AlphaFoldDB; A0A119UQD1; -.
DR Proteomes; UP000065504; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008668; F:(2,3-dihydroxybenzoyl)adenylate synthase activity; IEA:InterPro.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0019290; P:siderophore biosynthetic process; IEA:InterPro.
DR CDD; cd05920; 23DHB-AMP_lg; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR011963; DHB_AMP_lig.
DR NCBIfam; TIGR02275; DHB_AMP_lig; 1.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KWK69204.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..393
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 444..519
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 537 AA; 58143 MW; CF41073DA6BF394E CRC64;
MRAHGTPWPD AFADAYRAKG YWRGQSFAQW LDERVARHGE RIALVQDDIR WSYRTLGDEA
ARVARALTAR GIAPGDRVVV QLPNCVAFFA VTFALFRLGA LPVFALPAHR RREIGFFCRH
AQAVAYVAAE RHDGFDYRAL ARDVQADAPT LRHLLFTAPG NANLALADAP AHVALPPAPA
AGEVAFLQLS GGSTGTPKLI PRTHDDYLYS VRESARICAL SERSVYLAAL PAAHNYALSS
PGSFGVLHAG GTVVLCDGAS PDAAFPLIER ERVTVVALVP PLVPVWLAAV ERRREALASL
ELVQVGGARF DPALAARAAD GFGAQLQQVF GMAEGLVNYT RLDDPRELVT GTQGRPISPD
DEIRIVDDDD RPVAPGEVGH LLTRGPYTIR GYYEAHAHNA RAFTADGFYR TGDRVRVTAT
GHLIVEGRAK DQVNRGGEKI PAEEIEHLLL AHPGVVDAAL VPMPDPYLGE RSCAYVIRGT
PAPGAAELIR FVREQGVAAF KVPDRIEFVD AFPKTPVGKI DKRALRERIA AQLTTAA
//
