ID A0A120E5N4_9BASI Unreviewed; 536 AA.
AC A0A120E5N4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN ORFNames=RHOSPDRAFT_37249 {ECO:0000313|EMBL:KWU41221.1};
OS Rhodotorula sp. JG-1b.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=1305733 {ECO:0000313|EMBL:KWU41221.1, ECO:0000313|Proteomes:UP000062823};
RN [1] {ECO:0000313|EMBL:KWU41221.1, ECO:0000313|Proteomes:UP000062823}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JG-1b {ECO:0000313|EMBL:KWU41221.1,
RC ECO:0000313|Proteomes:UP000062823};
RG DOE Joint Genome Institute;
RA Goordial J., Raymond-Bouchard I., Riley R., Ronholm J., Shapiro N.,
RA Woyke T., Grigoriev I.V., Labutti K.M., Greer C., Whyte L., Bakermans C.;
RT "Draft genome of eurypsychrophile Rhodotorula sp. JG1b isolated from
RT permafrost in the hyper-arid Upper Elevation McMurdo Dry Valleys,
RT Antarctica.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; KQ954550; KWU41221.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A120E5N4; -.
DR STRING; 1305733.A0A120E5N4; -.
DR OrthoDB; 100792at2759; -.
DR Proteomes; UP000062823; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000062823}.
FT DOMAIN 22..243
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 346..494
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 536 AA; 59792 MW; 351C175E5B6D94E4 CRC64;
MLPTRVCRSV QASAALRSRV ARESYLKKVV KPQDLVHQFK DGQYIGWSGF TGVGYPKETP
LALAEHVEKN NLQGQLRFSL FVGASTGPEV EERWARNKMI ARRSPHQVGK AIAKGINSGE
IDFADKHLSM FPQDLTYGYY SLKRQGGEDG KMLDWAIVEA TEILPDGSIV PGASVGATPE
ILQTAEKIII EVNTSLPSFK GLHDITPSHM PPHRQPYLVQ NPSDRIGQVS VPVDPERVVA
IIETDKPDNT GQNAPETEDS KLIAQHLIQF LEDEVAVGRM PKNLHPLQSG IGNVANSIIA
GLRDSKFERL QVWTEVLQDS FLPLLNSGKL DFATATSIRF SPEMFKEFYR DWDQYQDKLL
LRPQQTANSP EIIRRLGVIG MNTPLEVDIY AHANSTNALG SRMLNGIGGS ADFLRNAKLS
VMHTPSSRPS KTDPTGISCI VPFATHVDQT EHDLDVIVTE QGLADVRGLS PRQRALVIIE
KCAHPDYRDQ LKEYYDRALH ECLKKGAGHE PHMLRNAFKM HLNFEKNGTM KIDKWD
//
