ID A0A120I877_PSEAA Unreviewed; 560 AA.
AC A0A120I877;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Tryptophan 2-monooxygenase {ECO:0000256|ARBA:ARBA00017871};
DE EC=1.13.12.3 {ECO:0000256|ARBA:ARBA00012535};
GN ORFNames=AWM79_00630 {ECO:0000313|EMBL:AMB83893.1};
OS Pseudomonas agarici.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=46677 {ECO:0000313|EMBL:AMB83893.1, ECO:0000313|Proteomes:UP000063229};
RN [1] {ECO:0000313|EMBL:AMB83893.1, ECO:0000313|Proteomes:UP000063229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2472 {ECO:0000313|EMBL:AMB83893.1,
RC ECO:0000313|Proteomes:UP000063229};
RA McClelland M., Jain A., Saraogi P., Mendelson R., Westerman R.,
RA SanMiguel P., Csonka L.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide;
CC Xref=Rhea:RHEA:16165, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:16031, ChEBI:CHEBI:16526, ChEBI:CHEBI:57912;
CC EC=1.13.12.3; Evidence={ECO:0000256|ARBA:ARBA00000112};
CC -!- PATHWAY: Plant hormone metabolism; auxin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004814}.
CC -!- SIMILARITY: Belongs to the tryptophan 2-monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00005833}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP014135; AMB83893.1; -; Genomic_DNA.
DR RefSeq; WP_060781915.1; NZ_CP014135.1.
DR AlphaFoldDB; A0A120I877; -.
DR STRING; 46677.AWM79_00630; -.
DR Proteomes; UP000063229; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0009851; P:auxin biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.405.40; -; 1.
DR Gene3D; 3.90.660.10; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR10742:SF342; AMINO_OXIDASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Auxin biosynthesis {ECO:0000256|ARBA:ARBA00023070};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033};
KW Reference proteome {ECO:0000313|Proteomes:UP000063229}.
FT DOMAIN 55..530
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 560 AA; 62109 MW; C9C81EF5E1C72840 CRC64;
MNQNSRHPAD GKKPITLFGP DFPFAFDDWI EHPAGLGSIP AHNHGAEVAI VGAGIAGLVA
AYELMKLGLK PVVYEASKMG GRLRSQAFEG AEGIIAELGG MRFPASSTAF YHYVDKLGLH
TKPFPNPLTP ASGSTVIDLE GQTHYAQKLS DLPALFQEVA DAWADALEEG SRFGDIQQAI
RDRNVPRLKE LWNTLVPLWD DRTFYDFIAT SKAFAKLSFR HREVFGQVGF GTGGWDSDFP
NSMLEIFRVV MTNCDDHQHL VVGGVEQVPL GIWRHVPPRC AHWPAGTSLS SLHHGAPRTG
VKRIDRAADG QFAVTDNWGD TRHYAAVLTT CQSWLLTTQI ECEESLFSQK MWMALDRTRY
MQSSKTFVMV DRPFWKDKDP QTGRDLMSMT LTDRLTRGTY LFDNGDDQPG VICLSYSWMS
DALKMLPQPI DKRVKLALDA LKKIYPKVDI AARIIGEPIT VSWEADPHFL GAFKGALPGH
YRYNQRMYAH FMQADMLAEQ RGIFIAGDDV SWTPAWVEGA VQTSLNAVWG IMNHFGGSSH
AENPGPGDVF AEIGPIALAD
//
