ID A0A120IAN4_9LACT Unreviewed; 2580 AA.
AC A0A120IAN4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Signal peptide-containing protein, YSIRK family {ECO:0000313|EMBL:SDL95604.1};
GN ORFNames=AWM75_00805 {ECO:0000313|EMBL:AMB98621.1}, SAMN04487985_10320
GN {ECO:0000313|EMBL:SDL95604.1};
OS Aerococcus urinaehominis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Aerococcus.
OX NCBI_TaxID=128944 {ECO:0000313|EMBL:AMB98621.1, ECO:0000313|Proteomes:UP000062260};
RN [1] {ECO:0000313|EMBL:AMB98621.1, ECO:0000313|Proteomes:UP000062260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG42038B {ECO:0000313|EMBL:AMB98621.1,
RC ECO:0000313|Proteomes:UP000062260};
RX PubMed=27103727;
RA Carkaci D., Dargis R., Nielsen X.C., Skovgaard O., Fuursted K.,
RA Christensen J.J.;
RT "Complete Genome Sequences of Aerococcus christensenii CCUG 28831T,
RT Aerococcus sanguinicola CCUG 43001T, Aerococcus urinae CCUG 36881T,
RT Aerococcus urinaeequi CCUG 28094T, Aerococcus urinaehominis CCUG 42038 BT,
RT and Aerococcus viridans CCUG 4311T.";
RL Genome Announc. 4:0-0(2016).
RN [2] {ECO:0000313|Proteomes:UP000062260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG42038B {ECO:0000313|Proteomes:UP000062260};
RA Carkaci D., Dargis R., Nielsen X.C., Skovgaard O., Fuursted K.,
RA Christensen J.J.;
RT "Six Aerococcus type strain genome sequencing and assembly using PacBio and
RT Illumina Hiseq.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SDL95604.1, ECO:0000313|Proteomes:UP000183325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15634 {ECO:0000313|EMBL:SDL95604.1,
RC ECO:0000313|Proteomes:UP000183325};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP014163; AMB98621.1; -; Genomic_DNA.
DR EMBL; FNHJ01000003; SDL95604.1; -; Genomic_DNA.
DR RefSeq; WP_067977280.1; NZ_FNHJ01000003.1.
DR STRING; 128944.AWM75_00805; -.
DR KEGG; auh:AWM75_00805; -.
DR OrthoDB; 2237783at2; -.
DR Proteomes; UP000062260; Chromosome.
DR Proteomes; UP000183325; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 3.10.20.890; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR044024; aRib.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR044055; RibLong.
DR InterPro; IPR028974; TSP_type-3_rpt.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; NF038186; YPDG_rpt; 2.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR PANTHER; PTHR10199; THROMBOSPONDIN; 1.
DR Pfam; PF18938; aRib; 1.
DR Pfam; PF05345; He_PIG; 1.
DR Pfam; PF08428; Rib; 1.
DR Pfam; PF18957; RibLong; 6.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SUPFAM; SSF103647; TSP type-3 repeat; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000062260};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2552..2574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2546..2580
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 62..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1807..1836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1937..1978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2074..2125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2212..2265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2349..2550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2084..2098
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2221..2235
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2358..2372
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2429..2443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2452..2466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2487..2520
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2580 AA; 280331 MW; EDFB246658ED8651 CRC64;
MLSRHNHKEW LRKQADRKTH FGLRKYSVGV VSVALSASLL FLGSQSLVQA QEVDASNLKS
LNQNQSSLSD PAEDANPIKP EADNSLVLEP VNNNQEASTE SPKPALKENS GEAEKDLKNP
EELTEIQPKD GQTLDGKPKT NPVADQNLDK NKATDNESAA DSDEIKAILS ESRSANLPNS
TSNDQDRASN SASGPLNQPV DWDKIKLPKV AGALSHHFFV TQGKNNLPGI SEADIAAEVL
RNEKVKEALT KAGLSADQVE VVLADKNELA KMTELVDDYG RRETAGTVKV YLKDKNSDNK
TATSDVKVFY YRPPFAAEVI KTEGQITNKP GEIPFNLTSH NIGKLVVKDP NNYTIAETER
DQLIKQFIKV NPQLNLSTEQ ISMDERGNLT IKNKAGEDPY QTVVNGDMFV SAIGQFPEVY
IFSTPDPDNP KNNKYSVLPG VEAQLRNGLN YTKFWGANGY GVPTNDKNAH LTGLKFKQEG
DKLKIFGTYD ESKSNDYGGS RVMGTYIGDH FTNSFSPFMI RILKIKNKSV IRSIDDPKQK
ITKADVEKAI EIDYEGLGPV YYNGVKNKWG LNGINSKTDL IKDIKNKVTK TVSIEEPAHE
VGIHQVTAEF TTDLVAKSGT ITENLIYYTE KVPNTLVDDP NNLKPVEIEA IRDKVAKTNK
VDPGKVTVKT DGTIQIKYGD RPGETVTFTK KPVITPTPSY EPVIGTPNQT IKIPAKILNG
NQLKQDHFTG PKFEKLADDP SFEIDKNTGE VRFTIPETSK DGDTITKSVK VSYQEGNRTV
EKTVEFTVKV TAQRDQYQGH YPPTKGNPGK AVNVIPPFFF EQDKQDGEPL DKAPTGTQFK
FDDKLPNNFS KKADNQLEVI IPDGGTDGQA TTVAVTLNSD GSLKVDLPEN IKDKTAIEVP
VLVTYQDGTS ETVTSKVTVS AQNQAYIPTY QAKDGKPGST VQLDKPNFTK DGQDAYKPAS
ASFAFPAHMC QNGQGQHTVK VDTVDGGKIE AVVTLGTDGQ VSIDLPKTAK DGTVVDIPVV
VKYGDGTQSE VKAQVNVVDQ SQRFKPSYTK QTIKPDTTVT VPAPNYGDNV PASATYKFGS
SVKPGKNGGH VIEVPSKDGG KIEATVTIND KDGSLTVHLP EGAQSGQPLQ VPVVVTYPDG
SEDQVTSDLV VKDDKQEYQA SYEPQTVQPG QKVTIEKPGF TDPKGLTTTP PADTSFQLDP
TMKKNDQGQT VVPVETTDGG TVEVPVTINQ DGSISLEIPD KAKHGTEIDV PVLVTYPDGG
QQKVNSKTTV SADNQQYPPK TEKVTKDFGE PVTEEELISK VKTDYPTTNP DKTVKVTIDD
PDALPKGDKP GDFTVPVTVT YPDGTKTKTS VAVTVKKQGL ANIKYIDKAT QSSATPTEID
AKFQVEKDPA KYPNTMTGKN GDKINLWDYE ISKAPQFIGF ENPTVQMKGG QHQYDNPATG
TILVAYDKID EITTEPKPGY VKVSFKAGDN AQLSDSDTKE VTYYVNPRAG VKIDFTNGGF
QLVGKDKNSN PLTKAVPQVT PNPGFKPNYA KEDQGSTSTW TFDNYHMVGQ DITSDLSFTS
QVSLSDQAKY EPDYDLVKVE KGQSATSQIK LYQTDNDHNF LAKDGQPIRD SQGQIVQDIN
KVTDKSQLAE VTPPATTNYS IAPNGITLAK DSKVDPSQIT VDPNTGTVTL PQSEVDKLAD
NEQVSVLVKV AYPDGSFDSA QAYFQRTIEP MTIEASVGKK TKVEGRDGTE VKDINVNVNK
DDAMIVASVP TLKYDEATKT ITGSLPKQDW QDGEESKDIT VKITAMRVRE DDEVETVETN
VVITVQRDTD LDGQPDINDT DDDKDGIPDD RETPGQEKVF TPLTMTAKVA QDKKVEGKNG
TPIDDIKVDI NKDGAQMVAS IPGLNYDENT GMVTGHLPKQ DWKDGEESKE VEIKLTANRL
GEDDKLETVE TTVTITVQRD TDGDGNPDVT DLDDDGDGIP DKDEIDKGSD PKDGKVIPQT
PLAPVAQAKV SPSEQTVVEK HAITPIEIAT DDPKAEISVD QLPAGLVYNP ETKTITGTPE
SPQWGDHETG ELVFLVKITN ADGSKPTKEV HITIQRDTDG DGQPDINDID DDNDGISDEE
ETNKGSDPKD GKVIPQTPLA PVAQAKVTPS KQTVVEKNYI EPIEITTEDP KAEISVDQLP
VGLVYNPETK TITGTPESPQ WGDHELGELV FLVKITNSDG SKLTKEVHIT IQRDTDGDGQ
PDINDIDDDN DGISDEEETT KGSGPKDGKV IPQTPLAPVA QAKVSPSEQI VVEKNYIEPI
EIKTEDPKAE ISVDQLPAGL VYNPETKTIT GTLESPQWGD HETGELVFLV KITNADGSKL
TKEVHITIQR DTDGDGNPDV TDLDDDGDGI EDKDDIEPKK YNVVTENGPG TSQPELPAFP
EDQVPPVSEN GPGTSQPELP VFPEDQVPPV SENGSSTTQP ELPVFPEDQV PSVSENGPST
SQPELPAFPE TELPAQPDQP GQTEKPVQPE KSDKPKGGKL PERSHKSEKP GQEKAPEKSS
QSDQIKGSAK VTRPDAQAGQ AHQPSLPATG SLASQTNLIA LSLLVSGSLM VFAYKRKEDR
//
