ID   A0A122IKF7_PLABE        Unreviewed;      1481 AA.
AC   A0A122IKF7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   08-NOV-2023, entry version 19.
DE   SubName: Full=Ribonuclease, putative {ECO:0000313|EMBL:CXI80074.1};
GN   ORFNames=PBK173_000343300 {ECO:0000313|EMBL:CXI80074.1};
OS   Plasmodium berghei.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX   NCBI_TaxID=5821 {ECO:0000313|EMBL:CXI80074.1, ECO:0000313|Proteomes:UP000069549};
RN   [1] {ECO:0000313|EMBL:CXI80074.1, ECO:0000313|Proteomes:UP000069549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K173 {ECO:0000313|EMBL:CXI80074.1,
RC   ECO:0000313|Proteomes:UP000069549};
RG   Pathogen Informatics;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT160032; CXI80074.1; -; Genomic_DNA.
DR   VEuPathDB; PlasmoDB:PBANKA_1230100; -.
DR   Proteomes; UP000069549; Chromosome 12.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   Gene3D; 2.40.50.690; -; 1.
DR   Gene3D; 2.40.50.700; -; 1.
DR   InterPro; IPR041505; Dis3_CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR022966; RNase_II/R_CS.
DR   PANTHER; PTHR23355:SF9; DIS3-LIKE EXONUCLEASE 2; 1.
DR   PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR   Pfam; PF17849; OB_Dis3; 1.
DR   Pfam; PF00773; RNB; 2.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR   PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE   4: Predicted;
FT   DOMAIN          688..1310
FT                   /note="Ribonuclease II/R"
FT                   /evidence="ECO:0000259|SMART:SM00955"
FT   REGION          386..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          458..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          913..940
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          959..1026
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..404
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        924..939
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        971..1023
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1481 AA;  173834 MW;  BC3121285887A550 CRC64;
     MCIYDEYITQ EKAIKGIISK KYIRGIINIR KLEYGYIIHE EEKIHIESKE DLNRAIDGDA
     VVVKLKNIND NKDIVKSNKI TGKVVYIEEH YGSTIQYVCI FRDKVKDRKY NVAIPFKKNI
     PLIQVRNNHI KEFMKKYNID DISNQLIYIK IFQWSPTEKF PEGKIIEILG QNDIFHNMQN
     AILLNHSLNF NLKDALEDQY LKDLKNKDNY INIITDELKK RMDLRQECVF TIDPETAKDL
     DDAINICKIN KKIIMNSNYY IKIMHNLMCH NGEIDETLLE QNLSLFVNND KEFFSKLKQN
     EYIKEIENIK HENFMKEKIT NANENQKVFE IDNYVDDKVT RQIEGIEKNL TRKQQIEKYK
     KMVIERKGFT NDEDYYASIK NEKMLKRKNG EDSHKKKKLK KTEKKKIQNN TGIASNTDIE
     TIIYDNCKTN KKFVNFNTNK FDKTMMNNDF KQVRNIKNLN NNSRSNSNNE ENLDEYSQFT
     KKNKSITIQE EKNKNLNNMD DNFNIQKLKK YNNKEKNIYK EKFEKSFLDI SSNQGNNSNE
     SENGEFFDKK NDFNLFVKDG NNDFSYLNNT VNKDWNTNKI STQIIGVKKI SNNEFFSNAT
     SRWNDDTSQS SINDIGMNEE NFEIGKVNTV GKGLKFYNTS MHSKNIECLS NISNNDGNNN
     DSKKGKGKNK YAYIFKQNRN KDIGSELYKD TDNYCAKCKK YITIDDIIKS MNSEKWRKYN
     LYEVGVHITD VSFFVKESTS LDIDARNRAM TIYLTHTCFP MLSRILSENL CSLDPINNRL
     CLSVFFYMDN SGKIDHNTFF IKETVIESKV KFTYEEVHSI VSGYVQLKKI INKLKKDEKD
     AFFSRNTNRE QSDKISQDPV EVRKVGSIVS NFSKMENDNR LVKNEHNEEF IKNSSSNDDI
     NLFDFNEKKK NYLDKTSTNC DNNEKQTTKK KDTNNNEKKS NSLYKRFLNL HFYSKKKNQS
     VVDVDSDSEK DLPFSPSSIT NMIIDKNHNT TTTTTTNNNN NNNNNNTTTN NNNNNNNNNK
     QKDLETPFES DIIIENKGKE MYSSSFNFEE ETNVKKKNGG IVMRKSDRNR INEKVLENEQ
     VRKGIEGIIK IFKNLNNKKH KLSQKEIINI TKMLYDMYKI TKGARSIRRK NGSLLFNNDK
     INFVLSNSCS PLGIVKKKNT FANYMIEELM LSANKLVAIR QYFSKYRDVS IFRSHNSSDS
     LNVSDIIELL KKHGIYFKVN SLAHILQFLD EKKNNFKKNK EKTSIFETVC AFVKKKMVRA
     EYHTYKYIKD NDMSTYHYAL SFLLYTHFTS PIRRYPDILV HRIIKRIIND ENQLKEKLCT
     SQEILSIVET PNVGIIENIC ENCNKCKARS KKAQMDCEIA FLCLYLQKHE TPGYNRGIIM
     DIQKDRASIF FKSFSFENTL FFTGTDKHHH KINKAHLKYL CNYTIQANVN KEEFTLIVYK
     QDAKTVKVRK VYKRFDYIPL YLFPLNSMPP SFFLAVAFSN K
//