ID   A0A124BXV9_ASPNG        Unreviewed;       320 AA.
AC   A0A124BXV9;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=NAD-binding phosphogluconate dehydrogenase {ECO:0000313|EMBL:GAQ43641.1};
GN   ORFNames=ABL_06302 {ECO:0000313|EMBL:GAQ43641.1};
OS   Aspergillus niger.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ43641.1, ECO:0000313|Proteomes:UP000068243};
RN   [1] {ECO:0000313|Proteomes:UP000068243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX   PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA   Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT   "Draft genome sequence of Aspergillus niger strain An76.";
RL   Genome Announc. 4:E0170015-E0170015(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAQ43641.1}.
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DR   EMBL; BCMY01000010; GAQ43641.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A124BXV9; -.
DR   PaxDb; 5061-CADANGAP00007685; -.
DR   VEuPathDB; FungiDB:An09g02920; -.
DR   VEuPathDB; FungiDB:ASPNIDRAFT2_1180702; -.
DR   VEuPathDB; FungiDB:ATCC64974_10640; -.
DR   VEuPathDB; FungiDB:M747DRAFT_342863; -.
DR   OMA; YAGINKG; -.
DR   Proteomes; UP000068243; Unassembled WGS sequence.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR015814; Pgluconate_DH_NAD-bd_C.
DR   Pfam; PF09130; DUF1932; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          8..140
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          214..284
FT                   /note="Phosphogluconate dehydrogenase NAD-binding putative
FT                   C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09130"
SQ   SEQUENCE   320 AA;  35196 MW;  414E84690959B03E CRC64;
     MSYPFEAIGI ISIGEMGLGI AQLLIAHHYR VLTYAADRSE ATQRRAWEAG IELRPSMQDL
     VDQSDCLLSI VPPRDALATA RRIVEASSAR PSVRDTPLWV IDLNAVSPKT AREIEALITE
     ASRTSSSSYL RYIDGGIVGG PPRPLQPTNP NEPAWHCPSL IVSGPGKLPD EKLSRTLNIK
     HISDQIGVAT GLKMCFASLT KGFFALAIQS FTTAHSMGVL PQLQELMEEY NAATLRIAEK
     GVVGMPPKAY RWVREMKEIG DTMRDDGGFE SDLFYAVAQV YQTVADDPIL GQEKPDDRQR
     GKTVEDVVEC LDKSLKVKKD
//