ID A0A124BYG8_ASPNG Unreviewed; 1245 AA.
AC A0A124BYG8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=GRAM domain protein {ECO:0000313|EMBL:GAQ45483.1};
GN ORFNames=ABL_08144 {ECO:0000313|EMBL:GAQ45483.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ45483.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the YSP2 family.
CC {ECO:0000256|ARBA:ARBA00006582}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ45483.1}.
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DR EMBL; BCMY01000016; GAQ45483.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A124BYG8; -.
DR PaxDb; 5061-CADANGAP00013179; -.
DR VEuPathDB; FungiDB:An17g00320; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1136410; -.
DR VEuPathDB; FungiDB:ATCC64974_64390; -.
DR VEuPathDB; FungiDB:M747DRAFT_39123; -.
DR OMA; PSGNMIS; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR23319:SF4; AT22714P-RELATED; 1.
DR PANTHER; PTHR23319; UNCHARACTERIZED; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1099..1118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 866..1038
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 1..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 794..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 819..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..306
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..783
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..836
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1245 AA; 133093 MW; DF35B7599876D945 CRC64;
MEANPIPEPP PVPETDIPSI SKVNRTKTTP VDLETMGSSS RSNGRSSIDS TSDRPKSQAG
EADSAKAGSS GFSKLLAARR KKKKDKNQKQ SDESSTQLET ESSKDVQESR STESRDGLST
TSSVGHENLS PPDHDTVNLL TDDSEPDRTP PLTSHNSHAG FYTSSSPLIR TTSVDETEED
GKGDAEAAAP ESQQETHGSS LNVPSDRGKK RGISPGRRFK NAFGSNPDKK ASNRDRAEST
SSSKSSRRGS LSAKRAQTVA EPPPPLPAPI RTDLKEDKPL PSLEIPAPRT PPHTAIPHPQ
TTVTPPTPNT EFPRLFISPD VTRSPDSIHS KDSPAGIIVS PSGNMISHRR VRSASAASHK
PSKLSNSISA IGPTIEETKA SAKSPGPMQT GFFSSVFSAA QNAASTLSSS LNSQSKGRNV
AQGGLNESES QPSAEGAPGP SQPINNKAEE KKPLAVDTLG SGDLDFSHLD IAIPPGGSVS
TPDGVVITKP DLPLEKRKVS QRDEEAARLE DSRAARAVTM AYEKPSETSL VPSTDDGLDL
QSSASFTKEG AGDQTPPSGS ILDGEIGHTR PYRSGSVRSR LARRRHRGSS AATTSTLGAI
GASAIALGAP AANASMPRLT GFAVASKKRN RDFHQLFRSV PEDDYLIEDY SCALQREIIL
AGRIYISEGH ICFSSNILGW VTTLVISFDE VVAIEKESTA MVFPNAIAIQ TLHARHTFRS
LLSRESTYDL MVNIWKINHP SLKSSANGTR VTDGTGDKTE KAGESDDESE EEDEIYDEDE
EGDNADSLFE AAGASVNGSD KSMPTKPVSR KASGALANAN GAGQAGANSS GDGKGSKSGS
PADGDTDFPG PPTHPPTEYT DPAGQYDKVV KDDVIPAPLG KVYSYVFGAQ SGAFMTKFLV
ENQKSGELQF ETGNKGLTND SRTRNYSYIK PLNGSIGPKQ TKCISTETLD FLDLEKAVLV
TLGTQTPDVP SGNVFLTKTK YLFTWAPNNQ TRFLMTCTIE WSGKSWLKGP IEKGAMDGQT
AFGNDLVAAL KAAVVPRGRT GGGKGKGKGR RKKSEVAQEA AAAAAKAAEE ERAQQANSWG
VLEPIHGVLG PVVDTVKPLL SGNVAIVLVG ILLFLLFFRR PSQPSVVSHD IGCPGYSLPQ
RLAAYEEMWR REESELWSWL EDRVGMDGLA IPTVSRSTGS RTQQYSRKVQ SERALASKVN
EEKMSDLEMD HAIRTTRERL DTLEKILLDR RSQPAADQAV VHSDL
//
