ID A0A124ECM2_9ACTN Unreviewed; 428 AA.
AC A0A124ECM2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KUH37968.1};
GN ORFNames=ATE80_15120 {ECO:0000313|EMBL:KUH37968.1};
OS Streptomyces kanasensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=936756 {ECO:0000313|EMBL:KUH37968.1, ECO:0000313|Proteomes:UP000054011};
RN [1] {ECO:0000313|EMBL:KUH37968.1, ECO:0000313|Proteomes:UP000054011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZX01 {ECO:0000313|EMBL:KUH37968.1,
RC ECO:0000313|Proteomes:UP000054011};
RA Zhang G., Han L., Feng J., Zhang X.;
RT "Genome-wide analysis reveals the secondary metabolome in Streptomyces
RT kanasensis ZX01.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUH37968.1}.
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DR EMBL; LNSV01000034; KUH37968.1; -; Genomic_DNA.
DR RefSeq; WP_058942735.1; NZ_LNSV01000034.1.
DR AlphaFoldDB; A0A124ECM2; -.
DR STRING; 936756.ATE80_15120; -.
DR OrthoDB; 3534856at2; -.
DR Proteomes; UP000054011; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR007168; Phageshock_PspC_N.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF65; SENSOR HISTIDINE KINASE COMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF04024; PspC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KUH37968.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054011};
KW Transferase {ECO:0000313|EMBL:KUH37968.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..73
FT /note="Phage shock protein PspC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04024"
FT DOMAIN 335..422
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
FT REGION 400..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..428
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 46066 MW; 0FA2AAF9230FD76A CRC64;
MPVAARPPET TEDPPVRRLY RSADGRMLGG VARGLAGHLG LPVVWVRLTF LGLFLADGPL
CVLLYAAFWI AVPLGIGGRS TEPRTVFATT PDGRRRLRRP DRGQVVALVA LLAGAAVFVG
TVDLGGEANR YVWPTLLVGV GVVLVWRQAD NARRARWSDS GRRKRLFQLA RGLAGVALVG
MGLTVFLVVR GSAAQLGTAL TAAIAVLAGM ALLAGPWLVR MSQDLSEERT MRIRAQERAE
VAAHVHDSVL HTLTLIQRNA EDPAEVRRLA RAQERELRNW LYRPEGTGKD EAEEPETLAE
AVKRAAAEVE DKHGVPLEVV VVGDCPLDEG LAAQMQAARE AMVNAAKYGG VGGAVQVYAE
VDGRTVFVSV RDRGPGFDLD AVPADRMGVR ESIIGRMRRH GGTARVRSAP GDGTEVELEM
DRAQEADG
//
