ID   A0A124H8N7_9ACTN        Unreviewed;      1312 AA.
AC   A0A124H8N7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Secretion protein EccC {ECO:0000313|EMBL:KUM82698.1};
GN   ORFNames=AQI94_38680 {ECO:0000313|EMBL:KUM82698.1};
OS   Streptomyces pseudovenezuelae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX   NCBI_TaxID=67350 {ECO:0000313|EMBL:KUM82698.1, ECO:0000313|Proteomes:UP000053039};
RN   [1] {ECO:0000313|EMBL:KUM82698.1, ECO:0000313|Proteomes:UP000053039}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40212 {ECO:0000313|EMBL:KUM82698.1,
RC   ECO:0000313|Proteomes:UP000053039};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces pseudovenezuelae DSM 40212, type
RT   strain for the species Streptomyces pseudovenezuelae.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM82698.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LMWM01000050; KUM82698.1; -; Genomic_DNA.
DR   RefSeq; WP_031038040.1; NZ_KQ948154.1.
DR   OrthoDB; 9807790at2; -.
DR   Proteomes; UP000053039; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR023836; EccCa-like_Actinobacteria.
DR   InterPro; IPR023837; EccCb-like_Actinobacteria.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR   NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR   PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR   PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR   Pfam; PF01580; FtsK_SpoIIIE; 2.
DR   SMART; SM00382; AAA; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR   PROSITE; PS50901; FTSK; 3.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        38..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          448..648
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   DOMAIN          806..998
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   DOMAIN          1094..1277
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   REGION          1278..1312
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1280..1312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         471..478
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT   BINDING         825..832
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT   BINDING         1111..1118
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ   SEQUENCE   1312 AA;  142879 MW;  DA858352A7A91867 CRC64;
     MSVVIVKRPP RVFPPEVPSE EVKLESPPEL PRTEDDSLLM NLLPMLGMGS SAAFFFMPGA
     QGFMKIMGGL MMVSTVAMLV AQIVRARKGP SGQMAEARRD YLKYLAQKRR EVRRTVHKQR
     DAQYYLHPAP EQLWALVAEG SRLWERRSMD PDFVQVRIGL GPQQLATPLV APDTAPVDEL
     EPLTAHAMQQ FIASYGTLGE LPLAIGLRSF YHVTISGDAE TVYGQTRSVV GQLASLHSPE
     DVVIAVVASP GAAVDWEWTK WLPHMQHKES DGAGTRRLLC YDLGELEEMI AHQLEGRPRW
     SRDGSPVLDQ PHVVVVLDGG GVPADSVLAS AEGLQGVTIL EVVPGELDEA RGSLSVRVWP
     DAMELEAGTG VFTGVPDVLS QAQAESLGRQ LAPLRLGAAD ADEPLLANLD FTDLMQIGDA
     ASVDVSRTWR PRTLHERLRV PIGLGESGEP VMLDLKEASQ EGMGPHGLCV GATGSGKSEL
     LRTLVLGLAV THSSETLNFV LADFKGGATF TGMGSMPHVS AVITNLADEL TLVDRMRDSI
     TGELTRRQEL LRTAGNYANI TDYEKARAAG AALDPLPSLV LIIDEFSELL AAKPDFIEMF
     IQIGRIGRSL GVHMLLASQR LEEGKLRGLD TFLSYRIGLR TFSAAESRTA IGVPDAYHLP
     NVPGAGILKY DTETMVQFKA AYVSGTYRPN GPMAQGGGRI DRSPVLFTAS PVPVRILTEP
     EPETRTHQVD DALADTVLDV IVSRLDGQGP PAHQVWLPPL DEPFSLDQVL PALGISPERG
     LHAEGYHLQS KLTVPVGLVD KPFEQRRDVM YADLSGSAGH ALIVGGPQSG KSTLVRTMIT
     SFALTHTPAE VQFYALDFGG GGMLALENLA HVGGAASRLD QEKVRRTVAE VHGILNAREE
     FFRSKSIDSM GTFRNRRAQG HYPDQQWGDV FLIIDGWATF KNDYEMLDPV IADIATRGLG
     FGVHLIITAT RYTEMRPALR DQILSRLELR LGDAMESEFD RKRAENVPMG KPGRGLSPDK
     LDYLAATPRI DGSTAVEDLA DGMAHLVQSV NNAWQGPTAP KVRMLPTMLH ASELPGGGDF
     GNRGIAVGVD ELTLSPVFVD FETDPLFVIY GESESGKSSL LRFMAKQISE RYAPNKALFV
     VSDFRRALLG QVPESHMYKY CASGPQLQEV MESLAGSMSR RMPGPDVTPD QLRNRSWYNE
     PDAFIFIDDY DLVATSMGNP MSVLLEYLPF ARDLGLRIIL ARSTSGASRS SFEPVLTRIK
     ELGAQGIVLS GDPSEGPVFN NIKATPQPQG RGQFISRRSS GQLVQTGYLP ES
//