ID A0A124HBQ1_9ACTN Unreviewed; 943 AA.
AC A0A124HBQ1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Dimethylmenaquinone methyltransferase {ECO:0000313|EMBL:KUM91957.1};
GN ORFNames=AQI88_34810 {ECO:0000313|EMBL:KUM91957.1};
OS Streptomyces cellostaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM91957.1, ECO:0000313|Proteomes:UP000054241};
RN [1] {ECO:0000313|EMBL:KUM91957.1, ECO:0000313|Proteomes:UP000054241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM91957.1,
RC ECO:0000313|Proteomes:UP000054241};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT for the species Streptomyces cellostaticus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM91957.1}.
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DR EMBL; LMWL01000067; KUM91957.1; -; Genomic_DNA.
DR RefSeq; WP_067007294.1; NZ_KQ948041.1.
DR AlphaFoldDB; A0A124HBQ1; -.
DR STRING; 67285.AQI88_34810; -.
DR OrthoDB; 9770306at2; -.
DR Proteomes; UP000054241; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR004017; Cys_rich_dom.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR Pfam; PF02754; CCG; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR Pfam; PF13183; Fer4_8; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:KUM91957.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054241};
KW Transferase {ECO:0000313|EMBL:KUM91957.1}.
FT DOMAIN 36..250
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 943 AA; 100767 MW; 4C096071EA718E2D CRC64;
MTDLSGLEAE LRGVVRGEVG FDVTARALVT MDASNYRRVP VGVVAPRDAD DVAAVLEVCR
ARGVPVVARG GGTSIAGQAT GTGVVLDFTR HLNGLLELDP ATRTAVVQPG LVLDRLQEAA
APHGLRFGPD PSTHSRCTLG GMIGNNSCGS HSVAWGTTAD SVRELSVITA RGQRLRLGRD
WAGAPDGLRE LAEGELARLR TGFPDLPRRI SGYALDALLP EKGADVARSF CGSEGTLGIL
TEAVVRLVEA PRARALAVLA YGDESAAAEA AAGLLPLGPL TVEGMAADLV RSRAGLPKGG
AWLFVETGGE TAAEARARAE AIVRAADVVD SLVVTDAAAQ RALWRIREDA SGTATRMPDG
SEAWPGWEDC AVPPARLGPY LRDFRALLAA HGLRGTPYGH FGDGCIHVRI DFDLLTEAGI
GRFRRFSEEL ADLVVAHGGS LSGEHGDGQA RAELLPRMYG EETVRLFERA KAAWDPDDLL
NPGMLVRPAP LDTNLRFSAL PPRPVDVAFG YPADGGDFRA AVRRCVGVAK CRTSTVAGPA
VMCPSFRATG EEEHSTRGRA RLLHEMLAGE LVTDGWRSTE VRDALDLCLS CKGCRSDCPV
GVDMATYKAE FLHHHYEGRR RPAAHYSMGW LPVWLRWVAR TRTAPLLNRL AAVRPFARLG
KRLGGIAPER EIPRVAPEPF SRWWRRRKRR TAGDLVVLWP DTFTEHLSPS VGQAAVRVLE
DAGLRVVLPP SRPFGGQVCC GLTYISTGQL DRARTVLRRT LDLMEPVLRR GAPVVVLEPS
CAAALRADLP ELLHDDPRAT RLASAVLTFA EALERHAPDW TPPAVNRPVA GQTHCHQHAV
LGDSADRRLR ASAGLSGELS GGCCGLAGNF GFEQGHFEVS KACAEEQLLP SVRDAAEGTV
VLADGFSCRT QLEQLAGVRG RHLAEVLAEG LETPGKDTGV GPG
//
