ID   A0A124HBS1_9ACTN        Unreviewed;       729 AA.
AC   A0A124HBS1;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Nitrite reductase {ECO:0000313|EMBL:KUM92137.1};
GN   ORFNames=AQI88_33725 {ECO:0000313|EMBL:KUM92137.1};
OS   Streptomyces cellostaticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM92137.1, ECO:0000313|Proteomes:UP000054241};
RN   [1] {ECO:0000313|EMBL:KUM92137.1, ECO:0000313|Proteomes:UP000054241}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM92137.1,
RC   ECO:0000313|Proteomes:UP000054241};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT   for the species Streptomyces cellostaticus.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM92137.1}.
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DR   EMBL; LMWL01000065; KUM92137.1; -; Genomic_DNA.
DR   RefSeq; WP_067006645.1; NZ_KQ948039.1.
DR   AlphaFoldDB; A0A124HBS1; -.
DR   STRING; 67285.AQI88_33725; -.
DR   OrthoDB; 7376058at2; -.
DR   Proteomes; UP000054241; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd00508; MopB_CT_Fdh-Nap-like; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 2.20.25.90; ADC-like domains; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   PANTHER; PTHR43105:SF15; FORMATE DEHYDROGENASE H; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054241}.
FT   DOMAIN          3..59
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
FT   REGION          535..575
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        540..555
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   729 AA;  77889 MW;  ADC5FCAB711B374D CRC64;
     METTSTPTHC PYCALQCGMN ITPLPQGGVE VTERPDFPVN RGALCGKGRT APEVLSSAVR
     LTSPLVRSGG RLVPASWEEA LGRIAERLGR TREQYGPDAL GVFGGGGLTN EKAYTLGKFA
     RVVLGTSQID YNGRFCMSSA AAAGTKAFGL DRGLPFPLED IPRTGCVILV GSNLAETMPP
     SLRFFSELRE NGGTLIVVDP RRTKTAEQAD LHLAPRPGTD LALALGLLHL VVAEGRTDED
     YIRERTAGWE EARAAAMGHW PEYVERITGV SVPQLREAVR LFCEPEAAMV LTARGPEQQS
     KGTDTVGAWI NLCLATGRAG RPLSGYGCLT GQGNGQGGRE HGQKADQLPG YRKLDDPAAR
     RHVAEVWGVD PDSLPGPGRS AYELLDALGT DIRSLLLMGS NPVVSAPRAA HIEERLRSLD
     FLAVCDVVLS ETAELADVVL PVTQWAEETG TTTSLEGRVL LRRQAISPPA GIHSDLYVLH
     DLAARLGVEK GFPTDPEEVF EELRRASAGG PADYSGITYR RLAQENGVFW PCPATTGVTD
     EDGEDGEDGE DTVLDGLPDD PARDAETAVP AVPSVHPGTP RLFLDRFATG DGRARFVAVA
     HRASGEEPDA EYPLLLTTGR VVAQYQSGAQ TRRVAELNAA APGPFVELHP RLAARLGAAE
     GDPLAVVSRR GRAVAPARIT TGIRPDTVFM PFHWPGEGRA NTLTNPALDP TSRMPEFKVC
     AVRVEAAES
//