ID A0A124HC75_9ACTN Unreviewed; 933 AA.
AC A0A124HC75;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KUM93546.1};
GN ORFNames=AQI88_26050 {ECO:0000313|EMBL:KUM93546.1};
OS Streptomyces cellostaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM93546.1, ECO:0000313|Proteomes:UP000054241};
RN [1] {ECO:0000313|EMBL:KUM93546.1, ECO:0000313|Proteomes:UP000054241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM93546.1,
RC ECO:0000313|Proteomes:UP000054241};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT for the species Streptomyces cellostaticus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM93546.1}.
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DR EMBL; LMWL01000047; KUM93546.1; -; Genomic_DNA.
DR RefSeq; WP_067003700.1; NZ_KQ948029.1.
DR AlphaFoldDB; A0A124HC75; -.
DR STRING; 67285.AQI88_26050; -.
DR OrthoDB; 9785847at2; -.
DR Proteomes; UP000054241; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF12697; Abhydrolase_6; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054241};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 7..414
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 582..660
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 659..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 933 AA; 101242 MW; 01E6CE364A1AAD3D CRC64;
MDELLEDDTP VVVGMACRFA GSDGLEEYWE RLRLGRSALG TTGRWAGEED AASFVGGFLD
GHQDFDARFF RVSPNEAQCM DPQQRILLQT VQHAVDDSYL TAADLRDLDC GVFVAGLPGD
YRSLVAQRSD IVYGTHSFLG NAPSTLSGRI SYFYDINGPS ITLDSACSSS LAALHEAVLN
VRAGQCRAAV VGAVSVFSTP EVLRFAQRSR MSSPEGASLP FTDAADGFVP AEGAASLVVM
RHDEARARGL RIYGAIQATG TNHNGTTNGL MAPSSRAQSR LIAELYEREK IDASQIAYLE
THGTGTPLGD PIELEGLRSA FRRAGSDGCH LGAVKPLIGH TLVASGLASV IKALLAFHHE
TIPPVSATDD AVSYLDVEPF RVNREPLPWP QDKPLCAISA FGFTGSNGHV VLRKLPDTPA
GEDAVDRRPG RALPFCLSAE SPGSLAALAQ RCRVLVAELP QDLLWDLSQL LLRRPRHTHE
QVVVARTRDE LLTGLDTLTR SDEDGPAPRT ADTNRLDDHL RDLVTHWRAQ DTPALQRRLD
APAGLARIAL PAYPFEKRRH WVIEEPPART PDTPQAEEVP EPVADGLVKQ LCAQLSALLG
YDEETDQVVP GTKIASLGLD SLSAVQLLSP YQKAGSAIKA HDLFRHETVA DLAAAIGGRP
LASPQETPQE PPARNDRGGP AADTARRASH RPPLTRWSEY GDSGRPTLLL PPLNCDRRAW
TQQIPALLRE GRKIYVPEYP GHQDAPFDEE RFSFEALADE VADFLRDTAD GPADLVGWSL
GGCISTLTAL RHPERVASLT LISCAPRYGE DAFERTLDLR EELRLHGGLL EAVFGEGGNL
AEKFSGNASM DILRCYYTAL TGFDIVDRLP DITADCLVVR GLGDCVLDTD TVAQYAQIPG
VQVREFEDHG HYVPLTAARS FNKTLTAFWA GRG
//
