ID A0A124HFH7_9ACTN Unreviewed; 501 AA.
AC A0A124HFH7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AQI95_20775 {ECO:0000313|EMBL:KUN03882.1};
OS Streptomyces yokosukanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67386 {ECO:0000313|EMBL:KUN03882.1, ECO:0000313|Proteomes:UP000053127};
RN [1] {ECO:0000313|EMBL:KUN03882.1, ECO:0000313|Proteomes:UP000053127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40224 {ECO:0000313|EMBL:KUN03882.1,
RC ECO:0000313|Proteomes:UP000053127};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces yokosukanensis DSM 40224, type
RT strain for the species Streptomyces yokosukanensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN03882.1}.
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DR EMBL; LMWN01000032; KUN03882.1; -; Genomic_DNA.
DR RefSeq; WP_067125529.1; NZ_KQ948213.1.
DR AlphaFoldDB; A0A124HFH7; -.
DR STRING; 67386.AQI95_20775; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000053127; Unassembled WGS sequence.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053127}.
FT DOMAIN 12..347
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 401..474
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 465..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 53573 MW; 6A8A677761A26789 CRC64;
MTEYAEELYE RFRAVAASAP DRTAVISGDG ARTTYRELAG LTDLATRALS ARTDGEDTVA
VEVERSPRHL AAVLAGWRLG LAYAPIRHHE TPARRSRVLR QLGGRALLVS GDARAARIGR
VDPREHGELT QPLRWPSGQA AYVVFTSGST GAPKGTVLSA EGFANRIDWS QRAYPLAADD
VLLQHTAVSF DFAVWETAAA LVHGATVLLT EDAPYADPEE AVQAAVRHRA TVAHFAPSVL
SLVELSGLLA DWTSLRLLYS GGEQLQSTLA SRVLDQAPHT RLVNQYGPAE TCVDSTHHPC
ALPLPEGPVP IGQAIDRTRL SLLPVDGLGS DAGELVICGP GVAFGYLDSA EPAGDRFGQD
SNGRTFRTGD VVRRLPDGEL LFLGRRDDQL KVGGVRVELG EIETVAAAVP GVSAAVACAV
DGPGGPVIDL VVESRDDSLD LRELRAALTE RLMGPVTPRR LRVVASLPRT PGGKVDRSRA
LDRARPDAEK THPVQTNEET R
//
