ID A0A124I344_9ACTN Unreviewed; 334 AA.
AC A0A124I344;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KUN82576.1};
GN ORFNames=AQJ64_18810 {ECO:0000313|EMBL:KUN82576.1};
OS Streptomyces griseoruber.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1943 {ECO:0000313|EMBL:KUN82576.1, ECO:0000313|Proteomes:UP000052982};
RN [1] {ECO:0000313|EMBL:KUN82576.1, ECO:0000313|Proteomes:UP000052982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40281 {ECO:0000313|EMBL:KUN82576.1,
RC ECO:0000313|Proteomes:UP000052982};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces griseoruber DSM 40281, type strain
RT for the species Streptomyces griseoruber.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN82576.1}.
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DR EMBL; LMWW01000031; KUN82576.1; -; Genomic_DNA.
DR RefSeq; WP_055637980.1; NZ_LIQS01000573.1.
DR AlphaFoldDB; A0A124I344; -.
DR STRING; 1943.AQJ64_18810; -.
DR Proteomes; UP000052982; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 334 AA; 35450 MW; 447F257E7F5A3A8C CRC64;
MAKITDVARR AGVSASTVSY ALSGKRPIST ATRQRVEAAA RELGYRPHAG ARALAGRRSN
VLALVAPLRA GIHVPVVMQF VASVVTAARR HDHDVLLLTQ EEGEDGLRRV ADTALVDALI
LMDVQLHDPR LPLLRTLDRP SVLIGFPRDC AGLTCIDLDF RSAGERCVEH LARLGHRVVA
LVGSPPEVYV RGTAFAQRVV QGFTAAADRG GLASAVHPCE ATPAAARQVA ERLLRDQPAL
TGVVVHNEAV LEPLVSAFEQ LGLRVPGDLS VAAICPDELA DRLHLTSVAL PSAEVGERAV
DLLMEKLAGG LVPEATLLQP TLNRRASTAA RTTA
//
